Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Study of the toxicological mechanism of acidified aerosols | |
| Tong, YP（童永彭）; Ni, XB; Zhang, YX（张元勋）; Chen, F; Zhang, GL（张桂林）; Ye, SH | |
| 2002 | |
| Source Publication | BIOLOGICAL TRACE ELEMENT RESEARCH
 |
| ISSN | 0163-4984 |
| Volume | 85Issue:2Pages:149 |
| Abstract | More than 30 aerosol samples were collected from I place near Zaojiaban Road (downtown of Shanghai) and 1 village near Jiading country (suburb) by a stacked-filter air sampler. The coarse particulates (>2.5 mum) and the fine particulates (PM2.5) and their unsoluble parts were analyzed by proton-induced X-ray emission. The cytotoxicity of particulates from the two places was evaluated by malondialdehyde (MDA) and thiazolyl blue (MTT) methods. The results show that the transition metal Fe, Cr, and Mn compounds from downtown are more easily soluble than those from the suburb, both in coarse and fine particulates, and the S content is much higher in particulates from downtown than that from the suburb. The cytotoxicity of the particulates from downtown is higher than that from the suburb and the cytotoxicity of acidified particulates is significantly higher than that of the controls. Because there are higher-soluble transition metal compounds that can induce free radicals in acidified particulates, the soluble transition metals may be one of the main factors for cytotoxicity. |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:000174280500005 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/10192 |
| Collection | 中科院上海原子核所2003年前 |
| Recommended Citation GB/T 7714 | Tong, YP,Ni, XB,Zhang, YX,et al. Study of the toxicological mechanism of acidified aerosols[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2002,85(2):149. |
| APA | Tong, YP,Ni, XB,Zhang, YX,Chen, F,Zhang, GL,&Ye, SH.(2002).Study of the toxicological mechanism of acidified aerosols.BIOLOGICAL TRACE ELEMENT RESEARCH,85(2),149. |
| MLA | Tong, YP,et al."Study of the toxicological mechanism of acidified aerosols".BIOLOGICAL TRACE ELEMENT RESEARCH 85.2(2002):149. |
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