Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope | |
| Wu, XH; Liu, WY; Ouyang, ZQ（欧阳振乾）; Li, MQ（李民乾） | |
| 1997 | |
| Source Publication | SCIENCE IN CHINA SERIES C-LIFE SCIENCES
 |
| ISSN | 1006-9305 |
| Volume | 40Issue:5Pages:458 |
| Abstract | The interaction between ribosome-inactivating proteins (RIPs) and supercoiled DNA was observed with an atomic force microscope (AFM). It was found that RIPs can bind to both supercoiled DNA and the unwound double-stranded loop region in supercoiled DNA. The RIPs bound to the supercoils can induce the conformational change of supercoiled DNA. Furthermore, the supercoiled DNA was relaxed and cleaved into nick or linear form by RIPs. It indicated that RIP seemed to be a supercoil-dependent DNA binding protein and exhibited the activity of supercoil-dependent DNA endonuclease. |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:A1997XU77200002 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/10256 |
| Collection | 中科院上海原子核所2003年前 |
| Recommended Citation GB/T 7714 | Wu, XH,Liu, WY,Ouyang, ZQ,et al. Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope[J]. SCIENCE IN CHINA SERIES C-LIFE SCIENCES,1997,40(5):458. |
| APA | Wu, XH,Liu, WY,Ouyang, ZQ,&Li, MQ.(1997).Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope.SCIENCE IN CHINA SERIES C-LIFE SCIENCES,40(5),458. |
| MLA | Wu, XH,et al."Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope".SCIENCE IN CHINA SERIES C-LIFE SCIENCES 40.5(1997):458. |
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