CAS OpenIR  > 中科院上海原子核所2003年前
Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope
Wu, XH; Liu, WY; Ouyang, ZQ(欧阳振乾); Li, MQ(李民乾)
1997
Source PublicationSCIENCE IN CHINA SERIES C-LIFE SCIENCES
ISSN1006-9305
Volume40Issue:5Pages:458
AbstractThe interaction between ribosome-inactivating proteins (RIPs) and supercoiled DNA was observed with an atomic force microscope (AFM). It was found that RIPs can bind to both supercoiled DNA and the unwound double-stranded loop region in supercoiled DNA. The RIPs bound to the supercoils can induce the conformational change of supercoiled DNA. Furthermore, the supercoiled DNA was relaxed and cleaved into nick or linear form by RIPs. It indicated that RIP seemed to be a supercoil-dependent DNA binding protein and exhibited the activity of supercoil-dependent DNA endonuclease.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:A1997XU77200002
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/10256
Collection中科院上海原子核所2003年前
Recommended Citation
GB/T 7714
Wu, XH,Liu, WY,Ouyang, ZQ,et al. Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope[J]. SCIENCE IN CHINA SERIES C-LIFE SCIENCES,1997,40(5):458.
APA Wu, XH,Liu, WY,Ouyang, ZQ,&Li, MQ.(1997).Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope.SCIENCE IN CHINA SERIES C-LIFE SCIENCES,40(5),458.
MLA Wu, XH,et al."Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope".SCIENCE IN CHINA SERIES C-LIFE SCIENCES 40.5(1997):458.
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