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放射性铼标记锡硫胶体制剂、制备方法及其应用
吴元芳; 李惠源; 董墨
Date Available2013-01-23
Country中国
Subtype发明专利
Abstract一种无载体188Re标记的锡硫胶体制剂,其制备方法分二步进行。首先,将无载体188Re高铼酸钠盐,硫代硫酸钠,明胶及氯化亚锡在酸性条件下反应形成酸性的188Re锡硫胶体;其次,用NaOH及Na2HPO4调pH值至6—7即成胶体制剂。188Re锡硫胶体制剂试用于荷人脑胶质瘤细胞的动物模型,证明其对肿瘤细胞的杀伤力强,放射性能长时间保留在肿瘤内,因此,188Re锡硫胶体制剂可应用于作为治疗人脑胶质瘤及其它肿瘤的放射性药物。
Subject AreaA61k51/12 ; //a61k103:10,121:00
Funding Project应物所课题组
Language中文
Status20060125 专利权的终止 未缴年费专利权终止
Application NumberCN98122047
Patent Agent费开逵
Document Type专利
Identifierhttp://ir.sinap.ac.cn/handle/331007/10405
Collection中科院上海原子核所2003年前
Recommended Citation
GB/T 7714
吴元芳,李惠源,董墨. 放射性铼标记锡硫胶体制剂、制备方法及其应用.
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