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[6,7-~3H]醋炔诺酮肟的合成
赵夏令; 周美英; 王国平; 彭庆义
1988-01-31
Source Publication核技术
Issue01
Abstract<正> 醋炔诺酮肟是新的避孕药物;其抗着床作用为炔诺酮的12.5倍。为研究它在体内药代动力学模型与过程;用多步有机反应合成了四个氚标记系列避孕药物:[6;7-~3H]炔诺醋(Ⅱ)、[6;7-~3H]醋炔诺酮(Ⅲ)、[6;7-~3H]炔诺酮肟(Ⅳ)和[6;7-~3H]醋炔诺酮肟(Ⅴ)。此外;还通过催化氚化还原反应合成了中间体[6;7-~3H]19-去甲基-4-雄烯-3;17-二酮(Ⅰ)和炔锂乙二胺络合物(固体)。
Indexed ByCNKI
Language中文
Funding Project原子核所项目组
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/10674
Collection中科院上海原子核所2003年前
Recommended Citation
GB/T 7714
赵夏令,周美英,王国平,等. [6,7-~3H]醋炔诺酮肟的合成[J]. 核技术,1988(01).
APA 赵夏令,周美英,王国平,&彭庆义.(1988).[6,7-~3H]醋炔诺酮肟的合成.核技术(01).
MLA 赵夏令,et al."[6,7-~3H]醋炔诺酮肟的合成".核技术 .01(1988).
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