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~(35)S 标记抗人肝癌单克隆抗体Hepama-1的制备
周桢堂; 庄道玲; 吴元芳; 张雨龙; 贺战军; 刘关福; 要福增
1998-08-20
Source Publication同位素
Issue03
Abstract采用H235SO4与苯胺合成35S-苯胺硫酸盐;经高温转换成35S-对氨基苯磺酸;然后再用碳二亚胺交联到抗人肝癌单克隆抗体Hepama-1上。所得35S-MAbHepama-1用Elisa方法检测仍保持良好的免疫活性。产品最高比活度可达51.8GBq/g;放化纯度>95%;放化产率以H235SO4投料计算最高可达27%;以35S-对氨基苯磺酸投料计算最高可达45%;适用于做荷瘤裸鼠动物模型放免治疗研究实验。
Indexed ByCNKI
Language中文
Funding Project原子核所项目组
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/10737
Collection中科院上海原子核所2003年前
Recommended Citation
GB/T 7714
周桢堂,庄道玲,吴元芳,等. ~(35)S 标记抗人肝癌单克隆抗体Hepama-1的制备[J]. 同位素,1998(03).
APA 周桢堂.,庄道玲.,吴元芳.,张雨龙.,贺战军.,...&要福增.(1998).~(35)S 标记抗人肝癌单克隆抗体Hepama-1的制备.同位素(03).
MLA 周桢堂,et al."~(35)S 标记抗人肝癌单克隆抗体Hepama-1的制备".同位素 .03(1998).
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