~3H－阿霉素及脑胶质瘤单抗的标记研究

CAS OpenIR > 中科院上海原子核所2003年前

	~3H－阿霉素及脑胶质瘤单抗的标记研究
	庄道玲; 吴元芳; 张雨龙; 兰青; 黄强
	1994-05-10
Source Publication	核技术
Issue	05
Abstract	用紫外光激活氚原子法对阿霉素标记;所得的３Ｈ一阿霉素仍具有生物活性;其比活度为９０ＴＢｑ／ｍｏｌ;然后用抗人脑胶质瘤单抗（ＭＡｂＳＺ－３９）通过多醛葡聚糖（ＰＡＤ）与３Ｈ一阿霉素桥联成３Ｈ一阿霉素一脑胶质瘤单抗免疫交联物;经凝胶柱（ＳｅｐｈａｄｅｘＧ－１００）纯化分离得纯品．其紫外吸收光谱与阿霉素单抗标准品的紫外吸收光谱相一致。动物实验证明;３Ｈ一阿霉素一脑胶质瘤单抗交联物在荷人脑胶质瘤棵小鼠瘤内高度浓集。
Indexed By	CNKI
Language	中文
Funding Project	原子核所项目组
Document Type	期刊论文
Identifier	http://ir.sinap.ac.cn/handle/331007/10767
Collection	中科院上海原子核所2003年前
Recommended Citation GB/T 7714	庄道玲,吴元芳,张雨龙,等. ~3H－阿霉素及脑胶质瘤单抗的标记研究[J]. 核技术,1994(05).
APA	庄道玲,吴元芳,张雨龙,兰青,&黄强.(1994).~3H－阿霉素及脑胶质瘤单抗的标记研究.核技术(05).
MLA	庄道玲,et al."~3H－阿霉素及脑胶质瘤单抗的标记研究".核技术 .05(1994).

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