CAS OpenIR  > 中科院上海原子核所2003年前
赵夏令; 刘景芝
Source Publication原子能科学技术
Abstract<正> 乙酰胆碱是人体内的重要神经传导介质。氚标记氯化乙酰胆碱可用来研究神经生理功能和大脑的思维与记忆功能。但氚标记的制备方法至今尚未见有文献报道。我们参照了碳-14标记的氯化乙酰胆碱的制备方法;设计了合成路线和安全简便的反应装置。首先合成了氚标记醋酸钠。然后与醋酸、醋酐共热进行基团交换。再将氚标记醋酸和醋酐与氯化胆碱发生乙酰化反应。经过分离纯化;得到高纯的氚标记氯化乙酰胆碱。放化纯度为99%;
Indexed ByCNKI
Funding Project原子核所项目组
Document Type期刊论文
Recommended Citation
GB/T 7714
赵夏令,刘景芝. 〔乙酰-~3H〕氯化乙酰胆碱的合成[J]. 原子能科学技术,1983(06).
APA 赵夏令,&刘景芝.(1983).〔乙酰-~3H〕氯化乙酰胆碱的合成.原子能科学技术(06).
MLA 赵夏令,et al."〔乙酰-~3H〕氯化乙酰胆碱的合成".原子能科学技术 .06(1983).
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