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碘-125标记甲状腺激素衍生物的合成
唐国忠; 赵夏令; 周美英; 殷林祥; 杨建忠; 胡根生
1992-01-31
Source Publication核技术
Issue01
Abstract以三碘甲腺原氨酸衍生物(T_3X)和Na~(125)I为原料;用氯胺-T法合成了~(125)I-T_3X和~(125)I-T_4X经HPLC分离纯化;产品的比活度:~(125)I-T_3X为16.87—31.78GBq/mg;~(125)I-T_4X为31.15—46.07GBq/mg。该二种示踪剂已用于直接法放射免疫分析测定血中游离T_3和游离T_4浓度;并已证明;该衍生物虽经化学改性限制了与血清中内源蛋白的结合.但仍保持了T_3、T_4原有的与相应特异性抗体的结合特性。
Indexed ByCNKI
Language中文
Funding Project原子核所项目组
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/11271
Collection中科院上海原子核所2003年前
Recommended Citation
GB/T 7714
唐国忠,赵夏令,周美英,等. 碘-125标记甲状腺激素衍生物的合成[J]. 核技术,1992(01).
APA 唐国忠,赵夏令,周美英,殷林祥,杨建忠,&胡根生.(1992).碘-125标记甲状腺激素衍生物的合成.核技术(01).
MLA 唐国忠,et al."碘-125标记甲状腺激素衍生物的合成".核技术 .01(1992).
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