CAS OpenIR  > 中科院上海原子核所2003年前
许玉杰; 李晴暖; 朱然; 朱本兴; 张勇平; 张晓东; 范我; 李文新
Source Publication苏州医学院学报
Abstract目的 研究俄歇电子发射体67Ga-EDTMP对人骨肉瘤细胞株 (HOS - 86 0 3)的辐射效应 ;探讨67Ga作为原发肿瘤和骨转移癌内照射治疗核素的可能性。方法 用成集落实验和透射电镜研究受照细胞的形态变化。结果 发现67Ga-EDTMP对肿瘤细胞有明显的杀伤和抑制增殖作用 ;并随剂量的加大 ;抑制效率增加 ;倒置显微镜下细胞集落数量减少 ;集落偏小 ;细胞稀疏。电镜下胞浆中空泡形成 ;细胞溶解、坏死 ;细胞核固缩 ;出现典型的细胞凋亡改变 ;形成凋亡小体。结论 67Ga可能是一种有前途的骨肉瘤和骨转移癌的放射性治疗核素
Indexed ByCNKI
Funding Project原子核所项目组
Document Type期刊论文
Recommended Citation
GB/T 7714
许玉杰,李晴暖,朱然,等. 俄歇电子发射体~(67)Ga-EDTMP对骨肉瘤细胞株辐射效应的形态学变化[J]. 苏州医学院学报,2000(12).
APA 许玉杰.,李晴暖.,朱然.,朱本兴.,张勇平.,...&李文新.(2000).俄歇电子发射体~(67)Ga-EDTMP对骨肉瘤细胞株辐射效应的形态学变化.苏州医学院学报(12).
MLA 许玉杰,et al."俄歇电子发射体~(67)Ga-EDTMP对骨肉瘤细胞株辐射效应的形态学变化".苏州医学院学报 .12(2000).
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