CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Carbon nanotube-based ultrasensitive multiplexing electrochemical immunosensor for cancer biomarkers
Wan, Y; Deng, WP; Su, Y; Zhu, XH; Peng, C(彭程); Hu, HY; Peng, HZ(彭红珍); Song, SP(宋世平); Fan, CH(樊春海)
2011
Source PublicationBIOSENSORS & BIOELECTRONICS
ISSN0956-5663
Volume30Issue:1Pages:93
AbstractA multiplexing electrochemical immunosensor was developed for ultrasensitive detection of cancer related protein biomarkers. We employed disposable screen-printed carbon electrode (SPCE) array as the detection platform. A universal multi-labeled nanoprobe was developed by loading HRP and goat-anti-rabbit IgG (secondary antibody, Ab(2)) onto multiwalled carbon nanotube (MWNT). This universal nanoprobe was available for virtually any sandwich-based antigen detection and showed superiority in several areas. By using the SPCE array and the universal nanoprobe, we could detect as low as 5 pg mL(-1) of prostate specific antigen (PSA) and 8 pg mL(-1) of Interleukin 8 (IL-8) with the electrochemical immunosensor. We also demonstrated simultaneous detection of two protein biomarkers with this platform. With these attracted features, our immunoassay system shows promising applications for in-field and point-of-care test in clinical diagnostics. (C) 2011 Elsevier B.V. All rights reserved.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000297610200014
Citation statistics
Cited Times:101[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/12848
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Wan, Y,Deng, WP,Su, Y,et al. Carbon nanotube-based ultrasensitive multiplexing electrochemical immunosensor for cancer biomarkers[J]. BIOSENSORS & BIOELECTRONICS,2011,30(1):93.
APA Wan, Y.,Deng, WP.,Su, Y.,Zhu, XH.,Peng, C.,...&Fan, CH.(2011).Carbon nanotube-based ultrasensitive multiplexing electrochemical immunosensor for cancer biomarkers.BIOSENSORS & BIOELECTRONICS,30(1),93.
MLA Wan, Y,et al."Carbon nanotube-based ultrasensitive multiplexing electrochemical immunosensor for cancer biomarkers".BIOSENSORS & BIOELECTRONICS 30.1(2011):93.
Files in This Item: Download All
File Name/Size DocType Version Access License
Carbon nanotube-base(347KB) 开放获取LicenseView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wan, Y]'s Articles
[Deng, WP]'s Articles
[Su, Y]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wan, Y]'s Articles
[Deng, WP]'s Articles
[Su, Y]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wan, Y]'s Articles
[Deng, WP]'s Articles
[Su, Y]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Carbon nanotube-based ultrasensitive multiplexing electrochemical immunosensor for cancer biomarkers.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.