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| Fast repair of the poly G hydroxyl radical adduct by two phenylpropanoid glycosides | |
| Huang, CY; Shi, YM; Wang, WF（王文锋）; Jia, ZJ; Wang, Y; Yao, SD(姚思德）; Lin, NY（林念芸）; Zheng, RL | |
| 2003 | |
| Source Publication | PHARMAZIE
 |
| ISSN | 0031-7144 |
| Volume | 58Issue:9 |
| Abstract | The repair activities and the reaction mechanisms of two phenylpropanoid glycosides (PPGs), isolated from a herb used in Chinese folk medicine, towards the oxidizing hydroxyl radical adduct of poly G were studied with a pulse radiolytic technique. On pulse irradiation of a nitrous oxide saturated 4 mM aqueous solution of poly G containing one of the tested compounds, the transient absorption spectrum of the hydroxyl radical adduct of poly G decays with the formation of that of the phenoxyl radical of the tested compound within several tens microseconds after the electron pulse irradiation. The results indicated that there was a repair reaction between the hydroxyl radical adduct of poly G and the compounds tested. The rate constants for the repair reactions of poly G hydroxyl radical adducts by verbasicoside and cistanoside C were determined to be 1.4 and 1.0 x 10(9) M(-1) . s(-1), respectively. |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 原子核所项目组 |
| WOS ID | WOS:000185425100016 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/12947 |
| Collection | 中科院上海原子核所2003年前 |
| Recommended Citation GB/T 7714 | Huang, CY,Shi, YM,Wang, WF,et al. Fast repair of the poly G hydroxyl radical adduct by two phenylpropanoid glycosides[J]. PHARMAZIE,2003,58(9). |
| APA | Huang, CY.,Shi, YM.,Wang, WF.,Jia, ZJ.,Wang, Y.,...&Zheng, RL.(2003).Fast repair of the poly G hydroxyl radical adduct by two phenylpropanoid glycosides.PHARMAZIE,58(9). |
| MLA | Huang, CY,et al."Fast repair of the poly G hydroxyl radical adduct by two phenylpropanoid glycosides".PHARMAZIE 58.9(2003). |
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