CAS OpenIR  > 中科院上海应用物理研究所2004-2010年
Epitaxial Growth of Trichosanthin Protein Crystals on Mica Surface
Sun, Li-Hua(孙丽华); Xu, Chun-Yan(徐春艳); Yu, Feng(郁峰); Tao, Shi-Xing(陶世兴); Li, Jian(李健); Zhou, Huan; Huang, Sheng(黄胜); Tang, Lin(唐琳); Hu, Jun(胡钧); He, Jian-Hua(何建华)
2010
Source PublicationCRYSTAL GROWTH & DESIGN
ISSN1528-7483
Volume10Issue:6Pages:2766
AbstractWe report the studies of epitaxial growth of trichosanthin (TCS) crystals on a mica substrate. TCS crystals grown on mica surface are found to be aligned well in four orientations, which was induced by the lattice of the mica substrate. The effect of potassium ions both at the mica surface and in solution was investigated by using different cation-modified surfaces and different precipitants. The results indicated that the binding of K(+) ions on the mica surface played a critical role in the epitaxial crystal growth of TCS. The high-resolution structures of crystals grown in different precipitants were solved by synchrotron radiation X-ray crystallography, and the K(+) binding sites in TCS crystals were identified. A strict lattice match between the TCS crystal and the mica substrate has been demonstrated based on the structural analysis of them. It reveals the mechanism of epitaxial nucleation and growth of TCS crystals. The experimental results provide new insights into the molecular mechanism of epitaxial growth and may open up the scope for the epitaxial crystal growth of proteins and other organic molecules.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000278147900046
Citation statistics
Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/13040
Collection中科院上海应用物理研究所2004-2010年
Recommended Citation
GB/T 7714
Sun, Li-Hua,Xu, Chun-Yan,Yu, Feng,et al. Epitaxial Growth of Trichosanthin Protein Crystals on Mica Surface[J]. CRYSTAL GROWTH & DESIGN,2010,10(6):2766.
APA Sun, Li-Hua.,Xu, Chun-Yan.,Yu, Feng.,Tao, Shi-Xing.,Li, Jian.,...&He, Jian-Hua.(2010).Epitaxial Growth of Trichosanthin Protein Crystals on Mica Surface.CRYSTAL GROWTH & DESIGN,10(6),2766.
MLA Sun, Li-Hua,et al."Epitaxial Growth of Trichosanthin Protein Crystals on Mica Surface".CRYSTAL GROWTH & DESIGN 10.6(2010):2766.
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