Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| The cytotoxicity of CdTe quantum dots and the relative contributions from released cadmium ions and nanoparticle properties | |
| Su, YY; Hu, M; Fan, CH（樊春海）; He, Y; Li, QN（李晴暖）; Li, WX（李文新）; Wang, LH（王丽华）; Shen, PP; Huang, Q（黄庆） | |
| 2010 | |
| Source Publication | BIOMATERIALS
 |
| ISSN | 0142-9612 |
| Volume | 31Issue:18Pages:4829 |
| Abstract | A systematic study was carried out on the relationship between the cytotoxicity of quantum dots (QDs) and free cadmium ions using CdCl(2) solution with known amounts of Cd(2+) as the control. We found that the CdTe QDs were more cytotoxic than CdCl(2) solutions even when the intracellular Cd(2+) concentrations were identical in HEK293 cells treated with them, implying the cytotoxicity of CdTe QDs cannot attributed solely to the toxic effect of free Cd(2+). Moreover, we discovered that the cytotoxicity of QDs was based on the concentration of total QDs ingested by cells. Our data clearly showed that specific properties of nanopartices have an obvious influence on their cytotoxicity. (C) 2010 Elsevier Ltd. All rights reserved. |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:000277783100006 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/13058 |
| Collection | 中科院上海应用物理研究所2004-2010年 |
| Recommended Citation GB/T 7714 | Su, YY,Hu, M,Fan, CH,et al. The cytotoxicity of CdTe quantum dots and the relative contributions from released cadmium ions and nanoparticle properties[J]. BIOMATERIALS,2010,31(18):4829. |
| APA | Su, YY.,Hu, M.,Fan, CH.,He, Y.,Li, QN.,...&Huang, Q.(2010).The cytotoxicity of CdTe quantum dots and the relative contributions from released cadmium ions and nanoparticle properties.BIOMATERIALS,31(18),4829. |
| MLA | Su, YY,et al."The cytotoxicity of CdTe quantum dots and the relative contributions from released cadmium ions and nanoparticle properties".BIOMATERIALS 31.18(2010):4829. |
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