CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Evaluation of chromium bioaccessibility in chromite ore processing residue using in vitro gastrointestinal method
Yu, SW; Du, JJ; Luo, T; Huang, YY(黄宇营); Jing, CY
2012
Source PublicationJOURNAL OF HAZARDOUS MATERIALS
ISSN0304-3894
Volume209
AbstractIncidental ingestion of Chromite ore processing residue (COPR) particles poses a potential health risk. The purpose of this study was to determine the Cr bioaccessibility from COPR using the in vitro gastrointestinal (IVG) procedure. The bioaccessible Cr(VI) was 53.8% and 42.9%, respectively, in the gastric and intestinal phases from a total of 19 490 mg kg(-1) Cr(VI) in COPR. Food intake including milk, dough, and ascorbic acid resulted in a significant decrease in Cr(VI) bioaccessibility. Some organic acids such as lactic, malic, and citric acid moderately reduced Cr(VI), while acetic acid exhibited no capacity for Cr(VI) reduction. The integrated area under the concentration-time curve (AUC) of the IVG extraction was used to calculate bioaccessibility. Compared with the bioaccessibility conventionally estimated using concentrations at the end of the extraction (CEP), the AUC technique should be implemented to confirm the accuracy of the IVG method when reduction of Cr(VI) occurs during the extraction. The absence of Cr(VI) phases in extracted residues as evidenced by XANES and XRPD analysis confirmed the Cr(VI) release and Cr(VI) reduction by food and ascorbic acid. With readily bioaccessible Cr(VI) and rapid human uptake, reduction of Cr(VI) might not be as effective a detoxification pathway as initially thought. (C) 2012 Elsevier B.V. All rights reserved.
Language英语
Funding Project应物所项目组
WOS IDWOS:000301884700031
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/13153
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Yu, SW,Du, JJ,Luo, T,et al. Evaluation of chromium bioaccessibility in chromite ore processing residue using in vitro gastrointestinal method[J]. JOURNAL OF HAZARDOUS MATERIALS,2012,209.
APA Yu, SW,Du, JJ,Luo, T,Huang, YY,&Jing, CY.(2012).Evaluation of chromium bioaccessibility in chromite ore processing residue using in vitro gastrointestinal method.JOURNAL OF HAZARDOUS MATERIALS,209.
MLA Yu, SW,et al."Evaluation of chromium bioaccessibility in chromite ore processing residue using in vitro gastrointestinal method".JOURNAL OF HAZARDOUS MATERIALS 209(2012).
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