Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection | |
He, SJ(何世江); Liu, KK; Su, S; Yan, J; Mao, XH; Wang, DF; He, Y; Li, LJ; Song, SP(宋世平); Fan, CH(樊春海) | |
2012 | |
Source Publication | ANALYTICAL CHEMISTRY
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ISSN | 0003-2700 |
Volume | 84Issue:10 |
Abstract | We have developed a surface-enhanced Raman scattering (SERS)-active substrate based on gold nanoparticle-decorated chemical vapor deposition (CVD)-growth graphene and used it for multiplexing detection of DNA. Due to the combination of gold nanoparticles and graphene, the Raman signals of dye were dramatically enhanced by this novel substrate. With the gold nanoparticles, DNA capture probes could be easily assembled on the surface of graphene films which have a drawback to directly immobilize DNA. This platform exhibits extraordinarily high sensitivity and excellent specificity for DNA detection. A detection limit as low as 10 pM is obtained. Importantly, two different DNA targets could be detected simultaneously on the same substrate just using one light source. |
Language | 英语 |
Funding Project | 应物所项目组 |
WOS ID | WOS:000303965500054 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.sinap.ac.cn/handle/331007/13178 |
Collection | 中科院上海应用物理研究所2011-2020年 |
Recommended Citation GB/T 7714 | He, SJ,Liu, KK,Su, S,et al. Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection[J]. ANALYTICAL CHEMISTRY,2012,84(10). |
APA | He, SJ.,Liu, KK.,Su, S.,Yan, J.,Mao, XH.,...&Fan, CH.(2012).Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection.ANALYTICAL CHEMISTRY,84(10). |
MLA | He, SJ,et al."Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection".ANALYTICAL CHEMISTRY 84.10(2012). |
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