CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection
He, SJ(何世江); Liu, KK; Su, S; Yan, J; Mao, XH; Wang, DF; He, Y; Li, LJ; Song, SP(宋世平); Fan, CH(樊春海)
2012
Source PublicationANALYTICAL CHEMISTRY
ISSN0003-2700
Volume84Issue:10
AbstractWe have developed a surface-enhanced Raman scattering (SERS)-active substrate based on gold nanoparticle-decorated chemical vapor deposition (CVD)-growth graphene and used it for multiplexing detection of DNA. Due to the combination of gold nanoparticles and graphene, the Raman signals of dye were dramatically enhanced by this novel substrate. With the gold nanoparticles, DNA capture probes could be easily assembled on the surface of graphene films which have a drawback to directly immobilize DNA. This platform exhibits extraordinarily high sensitivity and excellent specificity for DNA detection. A detection limit as low as 10 pM is obtained. Importantly, two different DNA targets could be detected simultaneously on the same substrate just using one light source.
Language英语
Funding Project应物所项目组
WOS IDWOS:000303965500054
Citation statistics
Cited Times:153[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/13178
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
He, SJ,Liu, KK,Su, S,et al. Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection[J]. ANALYTICAL CHEMISTRY,2012,84(10).
APA He, SJ.,Liu, KK.,Su, S.,Yan, J.,Mao, XH.,...&Fan, CH.(2012).Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection.ANALYTICAL CHEMISTRY,84(10).
MLA He, SJ,et al."Graphene-Based High-Efficiency Surface-Enhanced Raman Scattering-Active Platform for Sensitive and Multiplex DNA Detection".ANALYTICAL CHEMISTRY 84.10(2012).
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