Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction | |
| Wang, P(王萍); Ge, ZL(葛志磊); Pei, H; Wang, LH(王丽华); Fan, CH(樊春海) | |
| 2012 | |
| Source Publication | ACTA CHIMICA SINICA
 |
| ISSN | 0567-7351 |
| Volume | 70Issue:20 |
| Abstract | The hybridization chain reaction (HCR), a type of nucleic acid amplification method, was studied by a quartz crystal resonator technique. We probed the properties of the boundary DNA layer with a thickness of the viscous penetration depth at the crystal-solution interface. According to the relationship between the change of resonant frequency and the mass adsorbed on the crystal surface, the kinetics of surface-initiated HCR was measured, as well as the viscosity and the shear modulus of H1/H2 solution with different concentrations near a solid substrate. This work provides a new method for studying nucleic acid reactions at solid surface and mechanistic insight for HCR-based amplification and biodetection. |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:000311533600004 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/13269 |
| Collection | 中科院上海应用物理研究所2011-2020年 |
| Recommended Citation GB/T 7714 | Wang, P,Ge, ZL,Pei, H,et al. Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction[J]. ACTA CHIMICA SINICA,2012,70(20). |
| APA | Wang, P,Ge, ZL,Pei, H,Wang, LH,&Fan, CH.(2012).Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction.ACTA CHIMICA SINICA,70(20). |
| MLA | Wang, P,et al."Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction".ACTA CHIMICA SINICA 70.20(2012). |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| Quartz Crystal Micro（1112KB） | 开放获取 | CC BY-NC-SA | View Download | |||
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