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Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction | |
Wang, P(王萍); Ge, ZL(葛志磊); Pei, H; Wang, LH(王丽华); Fan, CH(樊春海) | |
2012 | |
Source Publication | ACTA CHIMICA SINICA
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ISSN | 0567-7351 |
Volume | 70Issue:20 |
Abstract | The hybridization chain reaction (HCR), a type of nucleic acid amplification method, was studied by a quartz crystal resonator technique. We probed the properties of the boundary DNA layer with a thickness of the viscous penetration depth at the crystal-solution interface. According to the relationship between the change of resonant frequency and the mass adsorbed on the crystal surface, the kinetics of surface-initiated HCR was measured, as well as the viscosity and the shear modulus of H1/H2 solution with different concentrations near a solid substrate. This work provides a new method for studying nucleic acid reactions at solid surface and mechanistic insight for HCR-based amplification and biodetection. |
Language | 英语 |
Funding Project | 应物所项目组 |
WOS ID | WOS:000311533600004 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.sinap.ac.cn/handle/331007/13269 |
Collection | 中科院上海应用物理研究所2011-2020年 |
Recommended Citation GB/T 7714 | Wang, P,Ge, ZL,Pei, H,et al. Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction[J]. ACTA CHIMICA SINICA,2012,70(20). |
APA | Wang, P,Ge, ZL,Pei, H,Wang, LH,&Fan, CH.(2012).Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction.ACTA CHIMICA SINICA,70(20). |
MLA | Wang, P,et al."Quartz Crystal Microbalance Studies on Surface-Initiated DNA Hybridization Chain Reaction".ACTA CHIMICA SINICA 70.20(2012). |
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Quartz Crystal Micro(1112KB) | 开放获取 | CC BY-NC-SA | View Download |
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