CAS OpenIR  > 中科院上海应用物理研究所2011-2020年
Ultrasound Effects on Assembly of Glucagon Fibrils
Tan, JH; Lin, DD; Pillai, S; Zhang, YY; Li, B(李宾); Zhou, XF
AbstractIn this work, we studied the ultrasound effect on the assembly of glucagon fibrils with Atomic force microscope (AFM) and fluorescence analysis. Experimental results showed that ultrasound can promote the formation of glucagon fibrils initially and thus drastically reduce the "lag time". The growth rate of fibrils as well as their morphologies was remarkably dependent on an applied ultrasonic power. With increasing incubation time, glucagon fibrils became ununiform and showed segment-like shapes when a low-power ultrasound (<100 W) was applied. While at the action of a high-power ultrasound (180 W) fibrils were broken gradually and therefore more and more fragments were visualized using AFM. Finally, the modulating mechanism of ultrasound on glucagon fibrils formation was also briefly discussed.
Funding Project应物所项目组
WOS IDWOS:000305252100002
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Document Type期刊论文
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GB/T 7714
Tan, JH,Lin, DD,Pillai, S,et al. Ultrasound Effects on Assembly of Glucagon Fibrils[J]. INTEGRATED FERROELECTRICS,2012,136.
APA Tan, JH,Lin, DD,Pillai, S,Zhang, YY,Li, B,&Zhou, XF.(2012).Ultrasound Effects on Assembly of Glucagon Fibrils.INTEGRATED FERROELECTRICS,136.
MLA Tan, JH,et al."Ultrasound Effects on Assembly of Glucagon Fibrils".INTEGRATED FERROELECTRICS 136(2012).
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