CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
A beveled working electrode coupled to a sandglass shape detection cell: A strategy to improve the sensitivity of electrochemiluminescence detection in microchip electrophoresis
Pan, Jianbin; Li, Xinchun; Chen, Zuanguang; Yang, Fan; Wu, Xiaohang; Li, Yinbao; Sun, Duanping; Yu, Yanyan
2013
Source PublicationELECTROCHIMICA ACTA
ISSN0013-4686
Volume90Pages:CONCATENATE(Sheet1!I2,-Sheet1!J2)
AbstractA beveled working electrode (WE) with a sandglass shape electrochemiluminescence (ECL) detection cell based on tris(2,2'-bipyridyl)ruthenium(II) (TBR) for microchip capillary electrophoresis (MCE) was described in this paper. The beveled WE was readily fabricated from a platinum (Pt) wire (0.3 mm diameter). The microchip comprised of three layers: top polydimethylsiloxane (PDMS) layer, middle glass plate, and bottom glass coverslip. The middle layer was a glass wafer on which the injection and separation channels were etched; meanwhile, an inverted funnel hole was made by a coniform drill, and a snot which was used to hold a guide tube aligning to the separation channel outlet was fabricated by a clubbed drill. The top layer was PDMS block containing four holes that connected injection channels and separation channel terminals, respectively. The two layers were bonded after their surfaces were processed by a plasma cleaner. The bottom layer was a coverslip (0.17 mm thick) which covered the inverted funnel hole in the middle layer with epoxy resin. The beveled WE was inserted into the guide tube and immobilized using melt adhesive. A Pt wire acted as a counter electrode (CE) was penetrated through the PDMS layer perpendicularly to the WE, with a 1.5-mm long portion left inside the detection cell. Proline was used to evaluate the developed MCE-ECL microdevice with the limit of detection down to 0.2 mu M (S/N = 3). The detection sensitivity was found to be improved remarkably, compared to the conventional disk electrode. (c) 2012 Elsevier Ltd. All rights reserved.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000316037600013
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/13646
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Pan, Jianbin,Li, Xinchun,Chen, Zuanguang,et al. A beveled working electrode coupled to a sandglass shape detection cell: A strategy to improve the sensitivity of electrochemiluminescence detection in microchip electrophoresis[J]. ELECTROCHIMICA ACTA,2013,90:CONCATENATE(Sheet1!I2,-Sheet1!J2).
APA Pan, Jianbin.,Li, Xinchun.,Chen, Zuanguang.,Yang, Fan.,Wu, Xiaohang.,...&Yu, Yanyan.(2013).A beveled working electrode coupled to a sandglass shape detection cell: A strategy to improve the sensitivity of electrochemiluminescence detection in microchip electrophoresis.ELECTROCHIMICA ACTA,90,CONCATENATE(Sheet1!I2,-Sheet1!J2).
MLA Pan, Jianbin,et al."A beveled working electrode coupled to a sandglass shape detection cell: A strategy to improve the sensitivity of electrochemiluminescence detection in microchip electrophoresis".ELECTROCHIMICA ACTA 90(2013):CONCATENATE(Sheet1!I2,-Sheet1!J2).
Files in This Item: Download All
File Name/Size DocType Version Access License
A beveled working el(918KB) 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Pan, Jianbin]'s Articles
[Li, Xinchun]'s Articles
[Chen, Zuanguang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Pan, Jianbin]'s Articles
[Li, Xinchun]'s Articles
[Chen, Zuanguang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Pan, Jianbin]'s Articles
[Li, Xinchun]'s Articles
[Chen, Zuanguang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: A beveled working electrode coupled to a sandglass shape detection cell. A strategy to improve the sensitivity of electrochemiluminescence detection in microchip electrophoresis.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.