Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Damage of DNA ends induced by mechanical force during AFM nano-manipulation | |
| Duan Na（段娜）; Wang Xinyan; Zhang Chen; Zhang Yi（张益）; Hu Jun（胡钧） | |
| 2013 | |
| Source Publication | NUCLEAR SCIENCE AND TECHNIQUES
 |
| ISSN | 1001-8042; 2210-3147 |
| Volume | 24Issue:1 |
| Abstract | An experimental and statistical study was carried out to explore the effects of mechanical forces on the ends of linear double-stranded DNA (dsDNA) fragments. Mechanical force was applied onto individual DNA molecules during atomic force microscope (AFM)-based picking-up manipulation. By comparing the PCR efficiency of two DNA fragments with primers either at ends or at the inner regions, it was found that the ends of DNA fragments were damaged during picking-up process. |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 应物所项目组 |
| WOS ID | WOS:000328921400006 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/13700 |
| Collection | 中科院上海应用物理研究所2011-2019年 |
| Recommended Citation GB/T 7714 | Duan Na,Wang Xinyan,Zhang Chen,et al. Damage of DNA ends induced by mechanical force during AFM nano-manipulation[J]. NUCLEAR SCIENCE AND TECHNIQUES,2013,24(1). |
| APA | Duan Na,Wang Xinyan,Zhang Chen,Zhang Yi,&Hu Jun.(2013).Damage of DNA ends induced by mechanical force during AFM nano-manipulation.NUCLEAR SCIENCE AND TECHNIQUES,24(1). |
| MLA | Duan Na,et al."Damage of DNA ends induced by mechanical force during AFM nano-manipulation".NUCLEAR SCIENCE AND TECHNIQUES 24.1(2013). |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| Damage of DNA ends i（366KB） | 开放获取 | CC BY-NC-SA | View Download | |||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment