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Fluorine-18 labeling by click chemistry: Multiple probes in one pot | |
Jia, Lina; Cheng, Zhen; Shi, Lingli; Li, Jianbo; Wang, Cheng; Jiang, Dawei; Zhou, Wei(周伟); Meng, Hu; Qi, Yujin(漆玉金); Cheng, Dengfeng; Zhang, Lan(张岚) | |
2013 | |
Source Publication | APPLIED RADIATION AND ISOTOPES
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ISSN | 0969-8043 |
Volume | 75Pages:CONCATENATE(Sheet1!I131,-Sheet1!J131) |
Abstract | Click chemistry has been widely applied in drug development including radiopharmaceuticals and has shown great advantages. Here we reported a novel strategy for rapid preparation of multiple F-18 labeled PET probes in one pot using the 'Click Reaction' of Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition of terminal alkynes and organic azides (CuAAC). Preliminary results showed its high efficiency and potential for speeding up the preclinical screening of PET probes. (C) 2013 Elsevier Ltd. All rights reserved. |
Indexed By | SCI |
Language | 英语 |
Funding Project | 应物所项目组 |
WOS ID | WOS:000317558900012 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.sinap.ac.cn/handle/331007/13754 |
Collection | 中科院上海应用物理研究所2011-2020年 |
Recommended Citation GB/T 7714 | Jia, Lina,Cheng, Zhen,Shi, Lingli,et al. Fluorine-18 labeling by click chemistry: Multiple probes in one pot[J]. APPLIED RADIATION AND ISOTOPES,2013,75:CONCATENATE(Sheet1!I131,-Sheet1!J131). |
APA | Jia, Lina.,Cheng, Zhen.,Shi, Lingli.,Li, Jianbo.,Wang, Cheng.,...&Zhang, Lan.(2013).Fluorine-18 labeling by click chemistry: Multiple probes in one pot.APPLIED RADIATION AND ISOTOPES,75,CONCATENATE(Sheet1!I131,-Sheet1!J131). |
MLA | Jia, Lina,et al."Fluorine-18 labeling by click chemistry: Multiple probes in one pot".APPLIED RADIATION AND ISOTOPES 75(2013):CONCATENATE(Sheet1!I131,-Sheet1!J131). |
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