CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration
Li, X.; Niu, Y.; Guo, H.; Chen, H.; Li, F.; Zhang, J.; Chen, W.; Wu, Z.; Deng, Y.; Wei, J.; Liu, C.
2013
Source PublicationJOURNAL OF INSTRUMENTATION
ISSN1748-0221
Volume8
AbstractThe regenerative treatment of large osseous defects remains a formidable challenge in today. In the present study, we have synthesized biodegradable magnesium calcium phosphate biocement (MCPB) scaffolds with interconnected macroporous structure (100-600 mu m), as well as good bioactivity, biocompatibility and proper degradatibility. The results revealed that the porosity increased from 52% to 80% of MCPB scaffolds while the compressive strength decreased from 6.1MPa to 1.2MPa. We further assessed the effects of scaffolds on the rabbit femur cavity defect model in vivo by using synchrotron radiation X-ray microCT and microCT imaging, indicating that the MCPB scaffolds underwent gradually degradation and promoted the extensive neo-bone formation.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000322572900010
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/13861
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Li, X.,Niu, Y.,Guo, H.,et al. Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration[J]. JOURNAL OF INSTRUMENTATION,2013,8.
APA Li, X..,Niu, Y..,Guo, H..,Chen, H..,Li, F..,...&Liu, C..(2013).Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration.JOURNAL OF INSTRUMENTATION,8.
MLA Li, X.,et al."Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration".JOURNAL OF INSTRUMENTATION 8(2013).
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