CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Pulse radiolysis and laser flash photolysis study of balofloxacin
Xu Yulie; Liu Yancheng; Li Haixia; Zhang Peng; Tang Ruizhi; Cao Xiyan; Wang Wenfeng
2013
Source PublicationNUCLEAR SCIENCE AND TECHNIQUES
ISSN1001-8042
Volume24
AbstractPulse radiolysis studies of the reactions between balofloxacin (BFX) and e(aq)(-), hydroxyl radical ((OH)-O-.), and N-3(.) were carried out to investigate the photosensitive toxicity of BFX. The BFX radical anion formed in the reaction of BFX with e(aq)(-) was located at 380 nm. The transient species formed in the reaction of BFX with (OH)-O-. radical were located in the region of 370 rim to 580 rim, with a maximum lambda(max) at 390 rim. The BFX radical cation was obtained by reacting BFX with N-3(.), and showed an absorption band at around 365 nm. The UV-Vis absorption of the BFX was found to be clearly dependent on pH. The pK(a) value of BFX was estimated to be 6.0 +/- 0.2. Under neutral conditions, the rate constants of BFX reacting with N-3(.) and e(aq)(-) were determined to be 1.3x10(10) dm(3.)mol(-1).s(-1) and 1.4x10(10) dm(3).mol(-1.)s(-1), respectively.
Indexed BySCI
Language英语
Funding Project应物所项目组
WOS IDWOS:000333376800015
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/13873
Collection中科院上海应用物理研究所2011-2019年
Recommended Citation
GB/T 7714
Xu Yulie,Liu Yancheng,Li Haixia,et al. Pulse radiolysis and laser flash photolysis study of balofloxacin[J]. NUCLEAR SCIENCE AND TECHNIQUES,2013,24.
APA Xu Yulie.,Liu Yancheng.,Li Haixia.,Zhang Peng.,Tang Ruizhi.,...&Wang Wenfeng.(2013).Pulse radiolysis and laser flash photolysis study of balofloxacin.NUCLEAR SCIENCE AND TECHNIQUES,24.
MLA Xu Yulie,et al."Pulse radiolysis and laser flash photolysis study of balofloxacin".NUCLEAR SCIENCE AND TECHNIQUES 24(2013).
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