Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Dynamic Covalent Diblock Copolymers: Instructed Coupling, Micellation and Redox Responsiveness | |
| Yang, QL; Bai, L; Zhang, YQ; Zhu, FX; Xu, YH; Shao, ZF; Shen, YM; Gong, B; yumeishen@sjtu.edu.cn; bgong@buffalo.edu | |
| 2014 | |
| Source Publication | MACROMOLECULES
 |
| ISSN | 0024-9297 |
| Volume | 47Issue:21Pages:7431—7441 |
| Abstract | Instructed by association units that allow reversible and unsymmetrical disulfide bond formation, hydrophilic (PEG) and hydrophobic (PLA) polymer chains are efficiently coupled into amphiphilic diblock copolymers. The desymmetrization of otherwise symmetrical reversible disulfide bond formation is achieved with amide association units that integrate both directional H-bonding and reversible disulfide bond formation, which ensure the connection of different polymer blocks while minimizing self-coupling. The resultant amphiphilic block copolymers self-assemble into long-lasting spherical micelles that are responsive to free thiols. |
| Keyword | Intracellular Drug-delivery Bonded Molecular Duplexes Supramolecular Polymers Block-copolymers Biomedical Applications Triblock Copolymers Aqueous-media Disulfide Micelles Design |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000344905800020 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/14095 |
| Collection | 中科院上海应用物理研究所2011-2020年 |
| Corresponding Author | yumeishen@sjtu.edu.cn; bgong@buffalo.edu |
| Recommended Citation GB/T 7714 | Yang, QL,Bai, L,Zhang, YQ,et al. Dynamic Covalent Diblock Copolymers: Instructed Coupling, Micellation and Redox Responsiveness[J]. MACROMOLECULES,2014,47(21):7431—7441. |
| APA | Yang, QL.,Bai, L.,Zhang, YQ.,Zhu, FX.,Xu, YH.,...&bgong@buffalo.edu.(2014).Dynamic Covalent Diblock Copolymers: Instructed Coupling, Micellation and Redox Responsiveness.MACROMOLECULES,47(21),7431—7441. |
| MLA | Yang, QL,et al."Dynamic Covalent Diblock Copolymers: Instructed Coupling, Micellation and Redox Responsiveness".MACROMOLECULES 47.21(2014):7431—7441. |
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| Dynamic Covalent Dib（2417KB） | 开放获取 | CC BY-NC-SA | View Download | |||
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