CAS OpenIR  > 中科院上海应用物理研究所2011-2019年
Effects of pH and polarity on the excited states of norfloxacin and its 4'-N-acetyl derivative: A steady-state and time-resolved study
Zhang, P; Li, HX; Yao, SD; Wang, WF; wangwenfeng@sinap.ac.cn
2014
Source PublicationSCIENCE CHINA-CHEMISTRY
ISSN1674-7291
Volume57Issue:3Pages:409—416
AbstractThe properties of norfloxacin (NFX) and its 4'-N-acetyl derivative (ANFX) are investigated in different pH aqueous solutions and H2O-CH3CN mixed solutions, to determine the effects of pH and polarity on their ground and excited states. The triplet states of NFX and ANFX are affected more by pH than by polarity. The pH dependence of the NFX and ANFX triplet states is likely due to the different quantum yields of different protonated forms. Steady-state fluorescence, time-resolved fluorescence, and laser flash photolysis experiments at different pH values provide clear evidence of the involvement of different intramolecular charge-transfer pathways in the singlet states of NFX and ANFX. The different electron-donating capacities of 1-N, 1'-N, and 4'-N under different conditions determine the major pathway.
KeywordFluoroquinolone Antibiotics Photophysical Properties Spectroscopic Properties Aqueous-solution Charge-transfer Photochemistry Dna Photolysis Toxicity
Indexed BySCI
Language英语
WOS IDWOS:000331980000010
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/14106
Collection中科院上海应用物理研究所2011-2019年
Corresponding Authorwangwenfeng@sinap.ac.cn
Recommended Citation
GB/T 7714
Zhang, P,Li, HX,Yao, SD,et al. Effects of pH and polarity on the excited states of norfloxacin and its 4'-N-acetyl derivative: A steady-state and time-resolved study[J]. SCIENCE CHINA-CHEMISTRY,2014,57(3):409—416.
APA Zhang, P,Li, HX,Yao, SD,Wang, WF,&wangwenfeng@sinap.ac.cn.(2014).Effects of pH and polarity on the excited states of norfloxacin and its 4'-N-acetyl derivative: A steady-state and time-resolved study.SCIENCE CHINA-CHEMISTRY,57(3),409—416.
MLA Zhang, P,et al."Effects of pH and polarity on the excited states of norfloxacin and its 4'-N-acetyl derivative: A steady-state and time-resolved study".SCIENCE CHINA-CHEMISTRY 57.3(2014):409—416.
Files in This Item: Download All
File Name/Size DocType Version Access License
Effects of pH and po(812KB) 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhang, P]'s Articles
[Li, HX]'s Articles
[Yao, SD]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhang, P]'s Articles
[Li, HX]'s Articles
[Yao, SD]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhang, P]'s Articles
[Li, HX]'s Articles
[Yao, SD]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Effects of pH and polarity on the excited states of norfloxacin and its 4'-N-acetyl derivative. A steady-state and time-resolved study.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.