CAS OpenIR  > 中科院上海应用物理研究所2011-2020年
Functional nanoprobes for ultrasensitive detection of biomolecules: an update
Xu, JJ; Zhao, WW; Song, SP; Fan, CH; Chen, HY; fchh@sinap.ac.cn; hychen@nju.edu.cn
2014
Source PublicationCHEMICAL SOCIETY REVIEWS
ISSN0306-0012
Volume43Issue:5Pages:1601—1611
AbstractWith the rapidly increasing demands for ultrasensitive biodetection, the design and applications of functional nanoprobes have attracted substantial interest for biosensing with optical, electrochemical, and various other means. In particular, given the comparable sizes of nanomaterials and biomolecules, there exists plenty of opportunities to develop functional nanoprobes with biomolecules for highly sensitive and selective biosensing. Over the past decade, numerous nanoprobes have been developed for ultrasensitive bioaffinity sensing of proteins and nucleic acids in both laboratory and clinical applications. In this review, we provide an update on the recent advances in this direction, particularly in the past two years, which reflects new progress since the publication of our last review on the same topic in Chem. Soc. Rev. The types of probes under discussion include: (i) nanoamplifier probes: one nanomaterial loaded with multiple biomolecules; (ii) quantum dots probes: fluorescent nanomaterials with high brightness; (iii) superquenching nanoprobes: fluorescent background suppression; (iv) nanoscale Raman probes: nanoscale surface-enhanced Raman resonance scattering; (v) nanoFETs: nanomaterial-based electrical detection; and (vi) nanoscale enhancers: nanomaterial-induced metal deposition.
KeywordEnhanced Raman-scattering Field-effect Transistor Semiconductor Quantum Dots Single-molecule Detection Messenger-rna Detection Graphene Oxide Gold Nanoparticles Signal Amplification Selective Detection Nucleic-acids
Indexed BySCI
Language英语
WOS IDWOS:000331188400014
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/14158
Collection中科院上海应用物理研究所2011-2020年
Corresponding Authorfchh@sinap.ac.cn; hychen@nju.edu.cn
Recommended Citation
GB/T 7714
Xu, JJ,Zhao, WW,Song, SP,et al. Functional nanoprobes for ultrasensitive detection of biomolecules: an update[J]. CHEMICAL SOCIETY REVIEWS,2014,43(5):1601—1611.
APA Xu, JJ.,Zhao, WW.,Song, SP.,Fan, CH.,Chen, HY.,...&hychen@nju.edu.cn.(2014).Functional nanoprobes for ultrasensitive detection of biomolecules: an update.CHEMICAL SOCIETY REVIEWS,43(5),1601—1611.
MLA Xu, JJ,et al."Functional nanoprobes for ultrasensitive detection of biomolecules: an update".CHEMICAL SOCIETY REVIEWS 43.5(2014):1601—1611.
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