CAS OpenIR  > 中科院上海应用物理研究所2011-2020年
Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification
Ouyang, XY; Li, J; Liu, HJ; Zhao, B; Yan, J; He, DN; Fan, CH; Chao, J; fchh@sinap.ac.cn; chaojie@sinap.ac.cn
2014
Source PublicationMETHODS
ISSN1046-2023
Volume67Issue:2Pages:198—204
AbstractDNA nanostructures have recently emerged as a type of drug delivery nanocarriers due to their suitable sizes, well-defined structures and low-toxicity. Here, we present a protocol for the assembly of DNA nanoribbon structures with rolling circle amplification (RCA) and delivery of CpG oligonucleotide. DNA nanoribbons with different dimensions and patterns were assembled with long RCA strands and several short staples. Significantly, we demonstrated they exhibited high-efficiency cellular uptake and improved immunostimulatory activity compared with ss- or ds- DNA. (C) 2013 Elsevier Inc. All rights reserved.
KeywordBacterial-dna Intracellular Delivery Gold Nanoparticles Cpg Motifs Platform Nanostructures Transport Origami Carrier Oligonucleotide
Indexed BySCI
Language英语
WOS IDWOS:000335623900013
Citation statistics
Cited Times:21[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/14381
Collection中科院上海应用物理研究所2011-2020年
Corresponding Authorfchh@sinap.ac.cn; chaojie@sinap.ac.cn
Recommended Citation
GB/T 7714
Ouyang, XY,Li, J,Liu, HJ,et al. Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification[J]. METHODS,2014,67(2):198—204.
APA Ouyang, XY.,Li, J.,Liu, HJ.,Zhao, B.,Yan, J.,...&chaojie@sinap.ac.cn.(2014).Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification.METHODS,67(2),198—204.
MLA Ouyang, XY,et al."Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification".METHODS 67.2(2014):198—204.
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