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Synchrotron-based X-ray microscopic studies for bioeffects of nanomaterials
Zhu, Y; Cai, XQ; Li, J; Zhong, ZT; Huang, Q; Fan, CH; ztzhong@hotmail.com; fchh@sinap.ac.cn
2014
Source PublicationNANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
ISSN1549-9634
Volume10Issue:3Pages:515—524
AbstractThere have been increasing interests in studying biological effects of nanomaterials, which are nevertheless faced up with many challenges due to the nanoscale dimensions and unique chemical properties of nanomaterials. Synchrotron-based X-ray microscopy, an advanced imaging technology with high spatial resolution and excellent elemental specificity, provides a new platform for studying interactions between nanomaterials and living systems. In this article, we review the recent progress of X-ray microscopic studies on bioeffects of nanomaterials in several living systems including cells, model organisms, animals and plants. We aim to provide an overview of the state of the art, and the advantages of using synchrotron-based X-ray microscopy for characterizing in vitro and in vivo behaviors and biodistribution of nanomaterials. We also expect that the use of a combination of new synchrotron techniques should offer unprecedented opportunities for better understanding complex interactions at the nano-biological interface and accounting for unique bioeffects of nanomaterials. From the Clinical Editor: Synchrotron-based X-ray microscopy is a non-destructive imaging technique that enables high resolution spatial mapping of metals with elemental level detection methods. This review summarizes the current use and perspectives of this novel technique in studying the biology and tissue interactions of nanomaterials. (C) 2014 Elsevier Inc. All rights reserved.
KeywordCucumber Cucumis-sativus Carbon Nanotubes Quantum Dots In-vivo Fluorescence Microscopy Caenorhabditis-elegans Ceria Nanoparticles Xanes Spectroscopy Tio2 Nanoparticles Model Organism
Indexed BySCI
Language英语
WOS IDWOS:000333812100003
Citation statistics
Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/14451
Collection中科院上海应用物理研究所2011-2019年
Corresponding Authorztzhong@hotmail.com; fchh@sinap.ac.cn
Recommended Citation
GB/T 7714
Zhu, Y,Cai, XQ,Li, J,et al. Synchrotron-based X-ray microscopic studies for bioeffects of nanomaterials[J]. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE,2014,10(3):515—524.
APA Zhu, Y.,Cai, XQ.,Li, J.,Zhong, ZT.,Huang, Q.,...&fchh@sinap.ac.cn.(2014).Synchrotron-based X-ray microscopic studies for bioeffects of nanomaterials.NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE,10(3),515—524.
MLA Zhu, Y,et al."Synchrotron-based X-ray microscopic studies for bioeffects of nanomaterials".NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 10.3(2014):515—524.
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