Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
Visualizing the three-dimensional mesoscopic structure of dermal tissues | |
Jiang, YZ; Tong, YJ; Lu, SL; 13901738685@139.com | |
2014 | |
Source Publication | JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
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ISSN | 1932-6254 |
Volume | 8Issue:10Pages:794—800 |
Abstract | Thorough knowledge of dermal tissue structure in three dimensions is not only a prerequisite for understanding the relationship between cells and their extracellular matrix, but also provides a basis for understanding of wound healing and scar formation for designing the ideal scaffold for skin tissue engineering. Here, we show for the first time the visualization of the three dimensional (3D) structure of dermal tissue by phase-contrast microtomography (mCT) with third-generation synchrotron radiation (SR). Compared with irregular dermal tissue (such as scar tissue), the normal dermal tissues were found to consist of a network of elliptically shaped regions containing a web of fibre bundles. The bundles, composed of fibres, were found to be orientated along specific directions, indicative of helical weaving. A regular array of dentate structure was shown on the fibres. The results showed that phase-contrast mCT with SR had a distinct advantage in accurately viewing the 3D microstructure of dermal tissues. Copyright (C) 2012 John Wiley & Sons, Ltd. |
Keyword | Regeneration Collagens Skin |
Indexed By | SCI |
Language | 英语 |
WOS ID | WOS:000343059700006 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.sinap.ac.cn/handle/331007/14551 |
Collection | 中科院上海应用物理研究所2011-2020年 |
Corresponding Author | 13901738685@139.com |
Recommended Citation GB/T 7714 | Jiang, YZ,Tong, YJ,Lu, SL,et al. Visualizing the three-dimensional mesoscopic structure of dermal tissues[J]. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE,2014,8(10):794—800. |
APA | Jiang, YZ,Tong, YJ,Lu, SL,&13901738685@139.com.(2014).Visualizing the three-dimensional mesoscopic structure of dermal tissues.JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE,8(10),794—800. |
MLA | Jiang, YZ,et al."Visualizing the three-dimensional mesoscopic structure of dermal tissues".JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8.10(2014):794—800. |
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