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Visualizing the three-dimensional mesoscopic structure of dermal tissues
Jiang, YZ; Tong, YJ; Lu, SL; 13901738685@139.com
2014
Source PublicationJOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
ISSN1932-6254
Volume8Issue:10Pages:794—800
AbstractThorough knowledge of dermal tissue structure in three dimensions is not only a prerequisite for understanding the relationship between cells and their extracellular matrix, but also provides a basis for understanding of wound healing and scar formation for designing the ideal scaffold for skin tissue engineering. Here, we show for the first time the visualization of the three dimensional (3D) structure of dermal tissue by phase-contrast microtomography (mCT) with third-generation synchrotron radiation (SR). Compared with irregular dermal tissue (such as scar tissue), the normal dermal tissues were found to consist of a network of elliptically shaped regions containing a web of fibre bundles. The bundles, composed of fibres, were found to be orientated along specific directions, indicative of helical weaving. A regular array of dentate structure was shown on the fibres. The results showed that phase-contrast mCT with SR had a distinct advantage in accurately viewing the 3D microstructure of dermal tissues. Copyright (C) 2012 John Wiley & Sons, Ltd.
KeywordRegeneration Collagens Skin
Indexed BySCI
Language英语
WOS IDWOS:000343059700006
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/14551
Collection中科院上海应用物理研究所2011-2020年
Corresponding Author13901738685@139.com
Recommended Citation
GB/T 7714
Jiang, YZ,Tong, YJ,Lu, SL,et al. Visualizing the three-dimensional mesoscopic structure of dermal tissues[J]. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE,2014,8(10):794—800.
APA Jiang, YZ,Tong, YJ,Lu, SL,&13901738685@139.com.(2014).Visualizing the three-dimensional mesoscopic structure of dermal tissues.JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE,8(10),794—800.
MLA Jiang, YZ,et al."Visualizing the three-dimensional mesoscopic structure of dermal tissues".JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8.10(2014):794—800.
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