Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo | |
| Li, LY; Wen, YL; Xu, Q; Xu, L; Liu, D; Liu, G; Huang, Q; Liu, G (reprint author), Shanghai Inst Measurement & Testing Technol, Shanghai 201800, Peoples R China. | |
| 2015 | |
| Source Publication | CURRENT PHARMACEUTICAL DESIGN
 |
| ISSN | 1381-6128 |
| Volume | 21Issue:22Pages:3191—3198 |
| Subtype | 期刊文献 |
| Abstract | Knocking down expression by small interfering RNA (siRNA) has shown high affinity, specificity and potency in silencing target gene sites. For effective endogenous RNA interference (RNAi), proper siRNA delivery vehicles are essential, to take the siRNA inside cells and protect them during the circulation. Carbon nanomaterials (CNMs) have been successfully applied in biomedicine and biosensor based on their ultra-high surface functionalization and nucleic acid molecular loading capacity. Recently, CNMs have drawn considerable research interest and expectation as potential non-viral vectors for siRNA delivery. Here we reviewed the recent application of CNMs in gene delivery for RNAi, mainly about fullerenes, carbon nanotubes (CNTs) and graphene. |
| Keyword | Efficient Intracellular Delivery Cationic Tetraamino Fullerene Functionalized Graphene Oxide Drug-delivery Sirna Delivery Biomedical Applications Photothermal Therapy Biosensing Platform Cellular Delivery Molecular Beacon |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000357937500014 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/24866 |
| Collection | 中科院上海应用物理研究所2011-2019年 |
| Corresponding Author | Liu, G (reprint author), Shanghai Inst Measurement & Testing Technol, Shanghai 201800, Peoples R China. |
| Recommended Citation GB/T 7714 | Li, LY,Wen, YL,Xu, Q,et al. Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo[J]. CURRENT PHARMACEUTICAL DESIGN,2015,21(22):3191—3198. |
| APA | Li, LY.,Wen, YL.,Xu, Q.,Xu, L.,Liu, D.,...&Liu, G .(2015).Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo.CURRENT PHARMACEUTICAL DESIGN,21(22),3191—3198. |
| MLA | Li, LY,et al."Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo".CURRENT PHARMACEUTICAL DESIGN 21.22(2015):3191—3198. |
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| Application of Carbo（307KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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