Improvement of bioactivity, degradability, and cytocompatibility of biocement by addition of mesoporous magnesium silicate into sodium-magnesium phosphate cement
Wu, YY; Tang, XF; Chen, J; Tang, TT; Guo, H; Tang, SC; Zhao, LM; Ma, XH; Hong, H; Wei, J; Hong, H (reprint author), E China Univ Sci & Technol, Minist Educ, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China.
2015
发表期刊JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
ISSN0957-4530
卷号26期号:9页码:
文章类型期刊文献
摘要A novel mesoporous magnesium-based cement (MBC) was fabricated by using the mixed powders of magnesium oxide, sodium dihydrogen phosphate, and mesoporous magnesium silicate (m-MS). The results indicate that the setting time and water absorption of the MBC increased as a function of increasing m-MS content, while compressive strength decreased. In addition, the degradability of the MBC in a solution of Tris-HCl and the ability of apatite formation on the MBC were significantly improved with the increase in m-MS content. In cell culture experiments, the results show that the attachment, proliferation, and alkaline phosphatase activity of the MC3T3-E1 cells on the MBC were significantly enhanced with the increase of the content of m-MS. It can be suggested that the MBC with good cytocompatibility could promote the proliferation and differentiation of the MC3T3-E1 cells. In short, our findings indicate that the MBC containing m-MS had promising potential as a new biocement for bone regeneration and repair applications.
关键词Chemically Bonded Ceramics Bone Regeneration In-vitro Ammonium Phosphate Compressive Strength Glass Scaffolds Cell Responses Calcium Precipitation Enhancement
语种英语
WOS记录号WOS:000361756500011
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/24952
专题中科院上海应用物理研究所2011-2018年
通讯作者Hong, H (reprint author), E China Univ Sci & Technol, Minist Educ, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China.
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GB/T 7714
Wu, YY,Tang, XF,Chen, J,et al. Improvement of bioactivity, degradability, and cytocompatibility of biocement by addition of mesoporous magnesium silicate into sodium-magnesium phosphate cement[J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,2015,26(9):—.
APA Wu, YY.,Tang, XF.,Chen, J.,Tang, TT.,Guo, H.,...&Hong, H .(2015).Improvement of bioactivity, degradability, and cytocompatibility of biocement by addition of mesoporous magnesium silicate into sodium-magnesium phosphate cement.JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,26(9),—.
MLA Wu, YY,et al."Improvement of bioactivity, degradability, and cytocompatibility of biocement by addition of mesoporous magnesium silicate into sodium-magnesium phosphate cement".JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 26.9(2015):—.
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