In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method

CAS OpenIR > 中科院上海应用物理研究所2011-2018年

	In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method
	Li, R; Wu, GZ; Ye, Y; Ye, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China.
	2015
发表期刊	APPLIED SURFACE SCIENCE
ISSN	0169-4332
卷号	356 页码:1221—1228
文章类型	期刊文献
摘要	Sulfonated polypropylene non-woven fabric (PPNWF) was successfully prepared via gamma-ray pre-irradiation-induced graft polymerization of sodium styrenesulfonate (SSS) and acrylamide (AAm). The effect of pre-irradiation dose, reaction temperature, reaction time and concentration of binary monomer on the degree of grafting (DG) was studied. The chemical structure of the original and modified PPNWF materials were investigated by attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) to confirm the successful introduction of sulfonated (-SO3-) group. The wettability was examined via measurement of de-ionized water adsorption percentage, which demonstrated that the hydrophilicity of PPNWF was greatly enhanced after graft modification. A little amount of bovine serum albumin (BSA) adsorption and nearly no platelet adhesion on the surface of modified PPNWF and low hemolytic ratio of the modified PPNWF revealed that the sulfonated PPNWF exhibited good hemocompatibility. Besides, blood clotting time measurement indicated that the anticoagulant property of PPNWF was effectively enhanced via SSS modification. Consequently, the hydrophilicity, in vitro hemocompatibility and anticoagulant effect of PPNWF were significantly improved by gamma-ray pre-irradiation-induced graft polymerization of SSS. (C) 2015 Published by Elsevier B.V.
关键词	Blood Compatibility Poly(Ethylene Oxide) Binary Monomers Citric-acid Side-chains Heparin Surface Polyurethane Membrane Polymer
语种	英语
WOS记录号	WOS:000365351600157
引用统计
文献类型	期刊论文
条目标识符	http://ir.sinap.ac.cn/handle/331007/24961
专题	中科院上海应用物理研究所2011-2018年
通讯作者	Ye, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China.
推荐引用方式 GB/T 7714	Li, R,Wu, GZ,Ye, Y,et al. In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method[J]. APPLIED SURFACE SCIENCE,2015,356:1221—1228.
APA	Li, R,Wu, GZ,Ye, Y,&Ye, Y .(2015).In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method.APPLIED SURFACE SCIENCE,356,1221—1228.
MLA	Li, R,et al."In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method".APPLIED SURFACE SCIENCE 356(2015):1221—1228.

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