In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method
Li, R; Wu, GZ; Ye, Y; Ye, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China.
2015
发表期刊APPLIED SURFACE SCIENCE
ISSN0169-4332
卷号356页码:1221—1228
文章类型期刊文献
摘要Sulfonated polypropylene non-woven fabric (PPNWF) was successfully prepared via gamma-ray pre-irradiation-induced graft polymerization of sodium styrenesulfonate (SSS) and acrylamide (AAm). The effect of pre-irradiation dose, reaction temperature, reaction time and concentration of binary monomer on the degree of grafting (DG) was studied. The chemical structure of the original and modified PPNWF materials were investigated by attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) to confirm the successful introduction of sulfonated (-SO3-) group. The wettability was examined via measurement of de-ionized water adsorption percentage, which demonstrated that the hydrophilicity of PPNWF was greatly enhanced after graft modification. A little amount of bovine serum albumin (BSA) adsorption and nearly no platelet adhesion on the surface of modified PPNWF and low hemolytic ratio of the modified PPNWF revealed that the sulfonated PPNWF exhibited good hemocompatibility. Besides, blood clotting time measurement indicated that the anticoagulant property of PPNWF was effectively enhanced via SSS modification. Consequently, the hydrophilicity, in vitro hemocompatibility and anticoagulant effect of PPNWF were significantly improved by gamma-ray pre-irradiation-induced graft polymerization of SSS. (C) 2015 Published by Elsevier B.V.
关键词Blood Compatibility Poly(Ethylene Oxide) Binary Monomers Citric-acid Side-chains Heparin Surface Polyurethane Membrane Polymer
语种英语
WOS记录号WOS:000365351600157
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/24961
专题中科院上海应用物理研究所2011-2018年
通讯作者Ye, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China.
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GB/T 7714
Li, R,Wu, GZ,Ye, Y,et al. In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method[J]. APPLIED SURFACE SCIENCE,2015,356:1221—1228.
APA Li, R,Wu, GZ,Ye, Y,&Ye, Y .(2015).In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method.APPLIED SURFACE SCIENCE,356,1221—1228.
MLA Li, R,et al."In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method".APPLIED SURFACE SCIENCE 356(2015):1221—1228.
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