CAS OpenIR  > 中科院上海应用物理研究所2011-2018年
In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method
Li, R; Wu, GZ; Ye, Y; Ye, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China.
2015
Source PublicationAPPLIED SURFACE SCIENCE
ISSN0169-4332
Volume356Pages:1221—1228
Subtype期刊文献
AbstractSulfonated polypropylene non-woven fabric (PPNWF) was successfully prepared via gamma-ray pre-irradiation-induced graft polymerization of sodium styrenesulfonate (SSS) and acrylamide (AAm). The effect of pre-irradiation dose, reaction temperature, reaction time and concentration of binary monomer on the degree of grafting (DG) was studied. The chemical structure of the original and modified PPNWF materials were investigated by attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) to confirm the successful introduction of sulfonated (-SO3-) group. The wettability was examined via measurement of de-ionized water adsorption percentage, which demonstrated that the hydrophilicity of PPNWF was greatly enhanced after graft modification. A little amount of bovine serum albumin (BSA) adsorption and nearly no platelet adhesion on the surface of modified PPNWF and low hemolytic ratio of the modified PPNWF revealed that the sulfonated PPNWF exhibited good hemocompatibility. Besides, blood clotting time measurement indicated that the anticoagulant property of PPNWF was effectively enhanced via SSS modification. Consequently, the hydrophilicity, in vitro hemocompatibility and anticoagulant effect of PPNWF were significantly improved by gamma-ray pre-irradiation-induced graft polymerization of SSS. (C) 2015 Published by Elsevier B.V.
KeywordBlood Compatibility Poly(Ethylene Oxide) Binary Monomers Citric-acid Side-chains Heparin Surface Polyurethane Membrane Polymer
Language英语
WOS IDWOS:000365351600157
Citation statistics
Cited Times:12[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/24961
Collection中科院上海应用物理研究所2011-2018年
Corresponding AuthorYe, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China.
Recommended Citation
GB/T 7714
Li, R,Wu, GZ,Ye, Y,et al. In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method[J]. APPLIED SURFACE SCIENCE,2015,356:1221—1228.
APA Li, R,Wu, GZ,Ye, Y,&Ye, Y .(2015).In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method.APPLIED SURFACE SCIENCE,356,1221—1228.
MLA Li, R,et al."In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method".APPLIED SURFACE SCIENCE 356(2015):1221—1228.
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