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| In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method | |
| Li, R; Wu, GZ; Ye, Y; Ye, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China. | |
| 2015 | |
| Source Publication | APPLIED SURFACE SCIENCE
 |
| ISSN | 0169-4332 |
| Volume | 356Pages:1221—1228 |
| Subtype | 期刊文献 |
| Abstract | Sulfonated polypropylene non-woven fabric (PPNWF) was successfully prepared via gamma-ray pre-irradiation-induced graft polymerization of sodium styrenesulfonate (SSS) and acrylamide (AAm). The effect of pre-irradiation dose, reaction temperature, reaction time and concentration of binary monomer on the degree of grafting (DG) was studied. The chemical structure of the original and modified PPNWF materials were investigated by attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) to confirm the successful introduction of sulfonated (-SO3-) group. The wettability was examined via measurement of de-ionized water adsorption percentage, which demonstrated that the hydrophilicity of PPNWF was greatly enhanced after graft modification. A little amount of bovine serum albumin (BSA) adsorption and nearly no platelet adhesion on the surface of modified PPNWF and low hemolytic ratio of the modified PPNWF revealed that the sulfonated PPNWF exhibited good hemocompatibility. Besides, blood clotting time measurement indicated that the anticoagulant property of PPNWF was effectively enhanced via SSS modification. Consequently, the hydrophilicity, in vitro hemocompatibility and anticoagulant effect of PPNWF were significantly improved by gamma-ray pre-irradiation-induced graft polymerization of SSS. (C) 2015 Published by Elsevier B.V. |
| Keyword | Blood Compatibility Poly(Ethylene Oxide) Binary Monomers Citric-acid Side-chains Heparin Surface Polyurethane Membrane Polymer |
| Language | 英语 |
| WOS ID | WOS:000365351600157 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/24961 |
| Collection | 中科院上海应用物理研究所2011-2019年 |
| Corresponding Author | Ye, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China. |
| Recommended Citation GB/T 7714 | Li, R,Wu, GZ,Ye, Y,et al. In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method[J]. APPLIED SURFACE SCIENCE,2015,356:1221—1228. |
| APA | Li, R,Wu, GZ,Ye, Y,&Ye, Y .(2015).In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method.APPLIED SURFACE SCIENCE,356,1221—1228. |
| MLA | Li, R,et al."In vitro hemocompatibility of sulfonated polypropylene non-woven fabric prepared via a facile gamma-ray pre-irradiation grafting method".APPLIED SURFACE SCIENCE 356(2015):1221—1228. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| In vitro hemocompati（2228KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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