CAS OpenIR  > 中科院上海应用物理研究所2011-2018年
Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines
Zhou, PP; Jia, SS; Pan, D; Wang, LH; Gao, JM; Lu, JX; Shi, JY; Tang, ZS; Liu, HJ; Tang, ZS (reprint author), Shanghai Jiao Tong Univ, Shanghai Key Lab Stomatol, Sch Med, Peoples Hosp 9,Dept Endodont, Shanghai 200011, Peoples R China.
2015
Source PublicationSCIENTIFIC REPORTS
ISSN2045-2322
Volume5Pages:
Subtype期刊文献
AbstractReversible catalysis regulation has gained much attention and traditional strategies utilized reversible ligand coordination for switching catalyst's conformations. However, it remains challenging to regulate the catalytic activity of metal nanoparticle-based catalysts. Herein, we report a new DNA nanomachine-driven reversible nano-shield strategy for circumventing this problem. The basic idea is based on the fact that the conformational change of surface-attached DNA nanomachines will cause the variation of the exposed surface active area on metal nanoparticles. As a proof-of-concept study, we immobilized G-rich DNA strands on gold nanoparticles (AuNPs) which have glucose oxidase (GOx) like activity. Through the reversible conformational change of the G-rich DNA between a flexible single-stranded form and a compact G-quadruplex form, the catalytic activity of AuNPs has been regulated reversibly for several cycles. This strategy is reliable and robust, which demonstrated the possibility of reversibly adjusting catalytic activity with external surface coverage switching, rather than coordination interactions.
KeywordEnzyme Cascade Reaction Machine Complex Nanotechnology Hybridization Selectivity Mimicking Chemistry Devices Growth
Language英语
WOS IDWOS:000361598200001
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/25032
Collection中科院上海应用物理研究所2011-2018年
Corresponding AuthorTang, ZS (reprint author), Shanghai Jiao Tong Univ, Shanghai Key Lab Stomatol, Sch Med, Peoples Hosp 9,Dept Endodont, Shanghai 200011, Peoples R China.
Recommended Citation
GB/T 7714
Zhou, PP,Jia, SS,Pan, D,et al. Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines[J]. SCIENTIFIC REPORTS,2015,5:—.
APA Zhou, PP.,Jia, SS.,Pan, D.,Wang, LH.,Gao, JM.,...&Tang, ZS .(2015).Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines.SCIENTIFIC REPORTS,5,—.
MLA Zhou, PP,et al."Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines".SCIENTIFIC REPORTS 5(2015):—.
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