CAS OpenIR  > 中科院上海应用物理研究所2011-2018年
An electrochemical immunosensor for quantitative detection of ficolin-3
San, LL; Zeng, DD; Song, SP; Zuo, XL; Zhang, H; Wang, CG; Wu, JR; Mi, XQ; Wu, JR (reprint author), Chinese Acad Sci, Shanghai Adv Res Inst, Lab Syst Biol, Shanghai 201210, Peoples R China.; Wu, JR (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Syst Biol, Shanghai 200031, Peoples R China.
2016
Source PublicationNANOTECHNOLOGY
ISSN0957-4484
Volume27Issue:25Pages:
Subtype期刊文献
AbstractDiabetes mellitus (DM) is one of the most common metabolic disorders in the world, of which more than 90% is type-2 diabetes mellitus (T2DM). There is a rather urgent need for reliable, sensitive and quick detection techniques in clinical application of T2DM. Ficolin-3 is a potential biomarker of T2DM, because serum ficolin-3 levels are associated with insulin resistance and predict the incidence of T2DM. Herein, a sandwich-type electrochemical immunosensor was developed for the detection of ficolin-3 in human serum. Cyclic voltammetry and the amperometric current versus time were used to characterize the performance of the immunosensor. Under optimal conditions, the detection limitation of ficolin-3 was 100 ng ml(-1) and the linear dynamic range was between 2 and 50 mu g ml(-1). The method has ideal accuracy, excellent stability and selectivity and has wide application prospects in clinical research.
KeywordSystemic-lupus-erythematosus Immune Component Ficolin-3 Type-2 Diabetes-mellitus Glassy-carbon Electrode Hakata Antigen Insulin-resistance Competitive Elisa Aflatoxin B-1 Serum-levels Identification
DOI10.1088/0957-4484/27/25/254003
Indexed BySCI
Language英语
WOS IDWOS:000377064200004
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/25643
Collection中科院上海应用物理研究所2011-2018年
Corresponding AuthorWu, JR (reprint author), Chinese Acad Sci, Shanghai Adv Res Inst, Lab Syst Biol, Shanghai 201210, Peoples R China.; Wu, JR (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Syst Biol, Shanghai 200031, Peoples R China.
Recommended Citation
GB/T 7714
San, LL,Zeng, DD,Song, SP,et al. An electrochemical immunosensor for quantitative detection of ficolin-3[J]. NANOTECHNOLOGY,2016,27(25):—.
APA San, LL.,Zeng, DD.,Song, SP.,Zuo, XL.,Zhang, H.,...&Wu, JR .(2016).An electrochemical immunosensor for quantitative detection of ficolin-3.NANOTECHNOLOGY,27(25),—.
MLA San, LL,et al."An electrochemical immunosensor for quantitative detection of ficolin-3".NANOTECHNOLOGY 27.25(2016):—.
Files in This Item: Download All
File Name/Size DocType Version Access License
An electrochemical i(1501KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[San, LL]'s Articles
[Zeng, DD]'s Articles
[Song, SP]'s Articles
Baidu academic
Similar articles in Baidu academic
[San, LL]'s Articles
[Zeng, DD]'s Articles
[Song, SP]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[San, LL]'s Articles
[Zeng, DD]'s Articles
[Song, SP]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: An electrochemical immunosensor for quantitative detection of ficolin-3.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.