Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
An electrochemical immunosensor for quantitative detection of ficolin-3 | |
San, LL; Zeng, DD; Song, SP; Zuo, XL; Zhang, H; Wang, CG; Wu, JR; Mi, XQ; Wu, JR (reprint author), Chinese Acad Sci, Shanghai Adv Res Inst, Lab Syst Biol, Shanghai 201210, Peoples R China.; Wu, JR (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Syst Biol, Shanghai 200031, Peoples R China. | |
2016 | |
发表期刊 | NANOTECHNOLOGY
![]() |
ISSN | 0957-4484 |
卷号 | 27期号:25页码:— |
文章类型 | 期刊文献 |
摘要 | Diabetes mellitus (DM) is one of the most common metabolic disorders in the world, of which more than 90% is type-2 diabetes mellitus (T2DM). There is a rather urgent need for reliable, sensitive and quick detection techniques in clinical application of T2DM. Ficolin-3 is a potential biomarker of T2DM, because serum ficolin-3 levels are associated with insulin resistance and predict the incidence of T2DM. Herein, a sandwich-type electrochemical immunosensor was developed for the detection of ficolin-3 in human serum. Cyclic voltammetry and the amperometric current versus time were used to characterize the performance of the immunosensor. Under optimal conditions, the detection limitation of ficolin-3 was 100 ng ml(-1) and the linear dynamic range was between 2 and 50 mu g ml(-1). The method has ideal accuracy, excellent stability and selectivity and has wide application prospects in clinical research. |
关键词 | Systemic-lupus-erythematosus Immune Component Ficolin-3 Type-2 Diabetes-mellitus Glassy-carbon Electrode Hakata Antigen Insulin-resistance Competitive Elisa Aflatoxin B-1 Serum-levels Identification |
DOI | 10.1088/0957-4484/27/25/254003 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000377064200004 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.sinap.ac.cn/handle/331007/25643 |
专题 | 中科院上海应用物理研究所2011-2018年 |
通讯作者 | Wu, JR (reprint author), Chinese Acad Sci, Shanghai Adv Res Inst, Lab Syst Biol, Shanghai 201210, Peoples R China.; Wu, JR (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Syst Biol, Shanghai 200031, Peoples R China. |
推荐引用方式 GB/T 7714 | San, LL,Zeng, DD,Song, SP,et al. An electrochemical immunosensor for quantitative detection of ficolin-3[J]. NANOTECHNOLOGY,2016,27(25):—. |
APA | San, LL.,Zeng, DD.,Song, SP.,Zuo, XL.,Zhang, H.,...&Wu, JR .(2016).An electrochemical immunosensor for quantitative detection of ficolin-3.NANOTECHNOLOGY,27(25),—. |
MLA | San, LL,et al."An electrochemical immunosensor for quantitative detection of ficolin-3".NANOTECHNOLOGY 27.25(2016):—. |
条目包含的文件 | 下载所有文件 | |||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
An electrochemical i(1501KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论