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题名:
DNA nanotechnology-enabled biosensors
作者: Chao, J; Zhu, D; Zhang, YN; Wang, LH; Fan, CH
刊名: BIOSENSORS & BIOELECTRONICS
出版日期: 2016
卷号: 76, 期号:-, 页码:68—79
关键词: ROLLING-CIRCLE AMPLIFICATION ; HYBRIDIZATION CHAIN-REACTION ; SEQUENCE-SPECIFIC DETECTION ; PROSTATE-SPECIFIC ANTIGEN ; CREATE NANOSCALE SHAPES ; NUCLEIC-ACIDS ; PHOTOELECTROCHEMICAL BIOSENSOR ; ELECTROCHEMICAL BIOSENSOR ; INTRACELLULAR DELIVERY ; BRANCHED JUNCTIONS
DOI: 10.1016/j.bios.2015.07.007
通讯作者: Fan, CH (reprint author), Chinese Acad Sci, Div Phys Biol, Shanghai 201800, Peoples R China.
文章类型: 期刊文献
英文摘要: Biosensors employ biological molecules to recognize the target and utilize output elements which can translate the biorecognition event into electrical, optical or mass-sensitive signals to determine the quantities of the target. DNA-based biosensors, as a sub-field to biosensor, utilize DNA strands with short oligonucleotides as probes for target recognition. Although DNA-based biosensors have offered a promising alternative for fast, simple and cheap detection of target molecules, there still exist key challenges including poor stability and reproducibility that hinder their competition with the current gold standard for DNA assays. By exploiting the self-recognition properties of DNA molecules, researchers have dedicated to make versatile DNA nanostructures in a highly rigid, controllable and fiinctionalized manner, which offers unprecedented opportunities for developing DNA-based biosensors. In this review, we will briefly introduce the recent advances on design and fabrication of static and dynamic DNA nanostructures, and summarize their applications for fabrication and functionalization of DNA-based biosensors. (C) 2015 Elsevier B.V. All rights reserved.
收录类别: SCI
语种: 英语
WOS记录号: WOS:000364895000007
ISSN号: 0956-5663
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinap.ac.cn/handle/331007/25689
Appears in Collections:中科院上海应用物理研究所2011-2017年_期刊论文

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Recommended Citation:
Chao, J,Zhu, D,Zhang, YN,et al. DNA nanotechnology-enabled biosensors[J]. BIOSENSORS & BIOELECTRONICS,2016-01-01,76(-):68—79.
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