Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage

doi:10.1016/j.carbon.2016.08.033

CAS OpenIR > 中科院上海应用物理研究所2011-2018年

	Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage
	Zhao, JF; Zhang, BW; Yu, CH; Liu, YC; Wang, WF; Li, JY; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
	2016
发表期刊	CARBON
ISSN	0008-6223
卷号	109 页码:487-494
文章类型	期刊论文
摘要	Oxidative damage of proteins or DNA strands induced by UV irradiation certainly brings inflammation, gene mutation, immunosuppression, even causes carcinogenesis to creatures. Here, we show that graphene oxide nanosheets (GONs) can significantly reduce the photosensitizer-mediated oxidative damage of proteins, caused by UV irradiation. GONs act as absorbers, physically shielding the proteins from UV light, but they participate in the photochemical reactions between photo-activated species and proteins as well. They quench transient species of photosensitizers by energy transfer and electron transfer, reduce highly toxic singlet oxygen yield and repair damaged protein residues. Our results may help revise and broaden previous findings concerning photochemical behavior and photo-biological effects of GONs. (C) 2016 Elsevier Ltd. All rights reserved.
DOI	10.1016/j.carbon.2016.08.033
收录类别	SCI
语种	英语
WOS记录号	WOS:000385900100056
引用统计
文献类型	期刊论文
条目标识符	http://ir.sinap.ac.cn/handle/331007/26523
专题	中科院上海应用物理研究所2011-2018年
通讯作者	Wang, WF; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
推荐引用方式 GB/T 7714	Zhao, JF,Zhang, BW,Yu, CH,et al. Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage[J]. CARBON,2016,109:487-494.
APA	Zhao, JF.,Zhang, BW.,Yu, CH.,Liu, YC.,Wang, WF.,...&Li, JY .(2016).Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage.CARBON,109,487-494.
MLA	Zhao, JF,et al."Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage".CARBON 109(2016):487-494.

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