Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage | |
| Zhao, JF; Zhang, BW; Yu, CH; Liu, YC; Wang, WF; Li, JY; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China. | |
| 2016 | |
| Source Publication | CARBON
 |
| ISSN | 0008-6223 |
| Volume | 109Pages:487-494 |
| Subtype | 期刊论文 |
| Abstract | Oxidative damage of proteins or DNA strands induced by UV irradiation certainly brings inflammation, gene mutation, immunosuppression, even causes carcinogenesis to creatures. Here, we show that graphene oxide nanosheets (GONs) can significantly reduce the photosensitizer-mediated oxidative damage of proteins, caused by UV irradiation. GONs act as absorbers, physically shielding the proteins from UV light, but they participate in the photochemical reactions between photo-activated species and proteins as well. They quench transient species of photosensitizers by energy transfer and electron transfer, reduce highly toxic singlet oxygen yield and repair damaged protein residues. Our results may help revise and broaden previous findings concerning photochemical behavior and photo-biological effects of GONs. (C) 2016 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.carbon.2016.08.033 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000385900100056 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/26523 |
| Collection | 中科院上海应用物理研究所2011-2020年 |
| Corresponding Author | Wang, WF; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China. |
| Recommended Citation GB/T 7714 | Zhao, JF,Zhang, BW,Yu, CH,et al. Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage[J]. CARBON,2016,109:487-494. |
| APA | Zhao, JF.,Zhang, BW.,Yu, CH.,Liu, YC.,Wang, WF.,...&Li, JY .(2016).Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage.CARBON,109,487-494. |
| MLA | Zhao, JF,et al."Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage".CARBON 109(2016):487-494. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| Graphene oxide_ A po（1353KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment