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题名:
Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage
作者: Zhao, JF; Zhang, BW; Yu, CH; Liu, YC; Wang, WF; Li, JY
刊名: CARBON
出版日期: 2016
卷号: 109, 页码:487-494
DOI: 10.1016/j.carbon.2016.08.033
通讯作者: Wang, WF ; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
文章类型: 期刊论文
英文摘要: Oxidative damage of proteins or DNA strands induced by UV irradiation certainly brings inflammation, gene mutation, immunosuppression, even causes carcinogenesis to creatures. Here, we show that graphene oxide nanosheets (GONs) can significantly reduce the photosensitizer-mediated oxidative damage of proteins, caused by UV irradiation. GONs act as absorbers, physically shielding the proteins from UV light, but they participate in the photochemical reactions between photo-activated species and proteins as well. They quench transient species of photosensitizers by energy transfer and electron transfer, reduce highly toxic singlet oxygen yield and repair damaged protein residues. Our results may help revise and broaden previous findings concerning photochemical behavior and photo-biological effects of GONs. (C) 2016 Elsevier Ltd. All rights reserved.
收录类别: SCI
语种: 英语
WOS记录号: WOS:000385900100056
ISSN号: 0008-6223
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinap.ac.cn/handle/331007/26523
Appears in Collections:中科院上海应用物理研究所2011-2017年_期刊论文

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Recommended Citation:
Zhao, JF,Zhang, BW,Yu, CH,et al. Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage[J]. CARBON,2016-01-01,109:487-494.
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