Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage
Zhao, JF; Zhang, BW; Yu, CH; Liu, YC; Wang, WF; Li, JY; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
2016
发表期刊CARBON
ISSN0008-6223
卷号109页码:487-494
文章类型期刊论文
摘要Oxidative damage of proteins or DNA strands induced by UV irradiation certainly brings inflammation, gene mutation, immunosuppression, even causes carcinogenesis to creatures. Here, we show that graphene oxide nanosheets (GONs) can significantly reduce the photosensitizer-mediated oxidative damage of proteins, caused by UV irradiation. GONs act as absorbers, physically shielding the proteins from UV light, but they participate in the photochemical reactions between photo-activated species and proteins as well. They quench transient species of photosensitizers by energy transfer and electron transfer, reduce highly toxic singlet oxygen yield and repair damaged protein residues. Our results may help revise and broaden previous findings concerning photochemical behavior and photo-biological effects of GONs. (C) 2016 Elsevier Ltd. All rights reserved.
DOI10.1016/j.carbon.2016.08.033
收录类别SCI
语种英语
WOS记录号WOS:000385900100056
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/26523
专题中科院上海应用物理研究所2011-2018年
通讯作者Wang, WF; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
推荐引用方式
GB/T 7714
Zhao, JF,Zhang, BW,Yu, CH,et al. Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage[J]. CARBON,2016,109:487-494.
APA Zhao, JF.,Zhang, BW.,Yu, CH.,Liu, YC.,Wang, WF.,...&Li, JY .(2016).Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage.CARBON,109,487-494.
MLA Zhao, JF,et al."Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage".CARBON 109(2016):487-494.
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