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Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative
Xue, Y; Liang, Z; Tan, H; Ni, L; Zhao, Z; Xiao, T; Xu, H; Xiao, T (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201204, Peoples R China.
2016
Source PublicationJOURNAL OF INSTRUMENTATION
ISSN1748-0221
Volume11Pages:-
Subtype期刊论文
AbstractAlthough a variety of methods, ranging from simple morphological examination to physical and chemical analysis, and DNA molecular biology, exist for authenticating Chinese medicinal materials(CMMs), no methods can achieve both the source species identification and quality evaluation of CMMs simultaneously. Furthermore, the methods that are currently available for the identification of CMMs, including both optical and electronic microscopy, usually entail strict requirements for sample preparation or testing environment, such as the slicing of super-thin sections, or processing with specific chemical reagents. These treatments not only damage the CMMs but may also cause some of the original microstructures to be missed. Additionally, they may even yield false results. Owing to the unique penetrating character of X-rays, X-ray phase contrast imaging(XPCI) can be used to realize the inner microstructures of CMMs through nondestructive imaging. With the higher flux and luminance of the third generation of synchrotron radiation facility, XPCI can provides clearer and finer microstructures of CMMs, which are mainly composed of C, H, O, and N elements, with better spatial and density resolutions. For more than ten years, the X-ray imaging group at the Shanghai Institute of Applied Physics has investigated the microstructures of CMMs by XPCI and they have established and developed a quantitative X-ray phase contrast micro-CT for investigating the characteristic microstructures of CMMs. During this period, a variety of typical CMMs have been investigated, from two-dimensional (2D) radiography to three-dimensional (3D) micro-CT, from qualitative to quantitative. Taken together, these results verify that quantitative X-ray phase contrast micro-CT is a practical tool for the microscopic investigation of CMMs. Additionally, further efforts are being made to find the relationship between the microstructures' quantitative factors and active chemical components. At present, experimental results have demonstrated that the quality of CMMs can be evaluated directly via the quantitative information of their characteristic microstructures.
KeywordComputerized Tomography (Ct) And Computed Radiography (Cr) X-ray Radiography And Digital Radiography (Dr)
DOI10.1088/1748-0221/11/07/C07001
Indexed BySCI
Language英语
WOS IDWOS:000379241100001
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/26572
Collection中科院上海应用物理研究所2011-2018年
Corresponding AuthorXiao, T (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201204, Peoples R China.
Recommended Citation
GB/T 7714
Xue, Y,Liang, Z,Tan, H,et al. Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative[J]. JOURNAL OF INSTRUMENTATION,2016,11:-.
APA Xue, Y.,Liang, Z.,Tan, H.,Ni, L.,Zhao, Z.,...&Xiao, T .(2016).Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative.JOURNAL OF INSTRUMENTATION,11,-.
MLA Xue, Y,et al."Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative".JOURNAL OF INSTRUMENTATION 11(2016):-.
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