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	Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative
	Xue, Y; Liang, Z; Tan, H; Ni, L; Zhao, Z; Xiao, T; Xu, H; Xiao, T (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201204, Peoples R China.
	2016
发表期刊	JOURNAL OF INSTRUMENTATION
ISSN	1748-0221
卷号	11页码:-
文章类型	期刊论文
摘要	Although a variety of methods, ranging from simple morphological examination to physical and chemical analysis, and DNA molecular biology, exist for authenticating Chinese medicinal materials(CMMs), no methods can achieve both the source species identification and quality evaluation of CMMs simultaneously. Furthermore, the methods that are currently available for the identification of CMMs, including both optical and electronic microscopy, usually entail strict requirements for sample preparation or testing environment, such as the slicing of super-thin sections, or processing with specific chemical reagents. These treatments not only damage the CMMs but may also cause some of the original microstructures to be missed. Additionally, they may even yield false results. Owing to the unique penetrating character of X-rays, X-ray phase contrast imaging(XPCI) can be used to realize the inner microstructures of CMMs through nondestructive imaging. With the higher flux and luminance of the third generation of synchrotron radiation facility, XPCI can provides clearer and finer microstructures of CMMs, which are mainly composed of C, H, O, and N elements, with better spatial and density resolutions. For more than ten years, the X-ray imaging group at the Shanghai Institute of Applied Physics has investigated the microstructures of CMMs by XPCI and they have established and developed a quantitative X-ray phase contrast micro-CT for investigating the characteristic microstructures of CMMs. During this period, a variety of typical CMMs have been investigated, from two-dimensional (2D) radiography to three-dimensional (3D) micro-CT, from qualitative to quantitative. Taken together, these results verify that quantitative X-ray phase contrast micro-CT is a practical tool for the microscopic investigation of CMMs. Additionally, further efforts are being made to find the relationship between the microstructures' quantitative factors and active chemical components. At present, experimental results have demonstrated that the quality of CMMs can be evaluated directly via the quantitative information of their characteristic microstructures.
关键词	Computerized Tomography (Ct) And Computed Radiography (Cr) X-ray Radiography And Digital Radiography (Dr)
DOI	10.1088/1748-0221/11/07/C07001
收录类别	SCI
语种	英语
WOS记录号	WOS:000379241100001
引用统计	被引频次：1[WOS]   [WOS记录]     [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.sinap.ac.cn/handle/331007/26572
专题	中科院上海应用物理研究所2011-2018年
通讯作者	Xiao, T (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201204, Peoples R China.
推荐引用方式 GB/T 7714	Xue, Y,Liang, Z,Tan, H,et al. Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative[J]. JOURNAL OF INSTRUMENTATION,2016,11:-.
APA	Xue, Y.,Liang, Z.,Tan, H.,Ni, L.,Zhao, Z.,...&Xiao, T .(2016).Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative.JOURNAL OF INSTRUMENTATION,11,-.
MLA	Xue, Y,et al."Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative".JOURNAL OF INSTRUMENTATION 11(2016):-.

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