Portable detection of clenbuterol using a smartphone-based electrochemical biosensor with electric field-driven acceleration
Dou, YZ; Jiang, ZN; Deng, WP; Su, J; Chen, SX; Song, HY; Aldalbahi, A; Zuo, XL; Song, SP; Shi, JY; Fan, CH; Fan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai 201800, Peoples R China.; Fan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Bioimaging Ctr, Shanghai Synchrotron Radiat Facil, Shanghai 201800, Peoples R China.
2016
发表期刊JOURNAL OF ELECTROANALYTICAL CHEMISTRY
ISSN1572-6657
卷号781页码:339-344
文章类型期刊论文
摘要We have developed a fast, highly sensitive and low-cost biosensing system for the detection of clenbuterol (CLB), using a homemade mobile electrochemical device with an electric field-driven acceleration strategy. This system consists of an embedded circuit in smartphone for signal processing and a screen-printed carbon electrode (SPCE) modified with multi-walled carbon nanotubes (MWNTs) and goat anti mouse-immunoglobulin G (IgG) sensing layer (MWNTs-I-layer). CLB monoclonal antibody was assembled through its binding to the surface confined antibody. Such modified electrodes were used for rapid and sensitive amperometric immunosensing detection of CLB. Horseradish peroxidase-coupled CLB (CLB-HRP) competed with free CLB in the samples to bind the monoclonal antibody. By using this mobile system, we could detect CLB ranging from 03 ng.mL(-1) to 100 ng.mL(-1) with the detection limit of 0.076 ng.mL(-1). The whole competitive-type detection process was finished within 6 min. We expect this device can meet the requirements for field detection of various food security-related species. (C) 2016 Elsevier B.V. All rights reserved.
关键词Electrochemistry Portable Sensor Smartphone Electrical Field
DOI10.1016/j.jelechem.2016.04.022
收录类别SCI
语种英语
WOS记录号WOS:000390494200052
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/26599
专题中科院上海应用物理研究所2011-2018年
通讯作者Song, SP; Fan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai 201800, Peoples R China.; Fan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Bioimaging Ctr, Shanghai Synchrotron Radiat Facil, Shanghai 201800, Peoples R China.
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Dou, YZ,Jiang, ZN,Deng, WP,et al. Portable detection of clenbuterol using a smartphone-based electrochemical biosensor with electric field-driven acceleration[J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY,2016,781:339-344.
APA Dou, YZ.,Jiang, ZN.,Deng, WP.,Su, J.,Chen, SX.,...&Fan, CH .(2016).Portable detection of clenbuterol using a smartphone-based electrochemical biosensor with electric field-driven acceleration.JOURNAL OF ELECTROANALYTICAL CHEMISTRY,781,339-344.
MLA Dou, YZ,et al."Portable detection of clenbuterol using a smartphone-based electrochemical biosensor with electric field-driven acceleration".JOURNAL OF ELECTROANALYTICAL CHEMISTRY 781(2016):339-344.
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