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题名: Portable detection of clenbuterol using a smartphone-based electrochemical biosensor with electric field-driven acceleration
作者: Dou, YZ; Jiang, ZN; Deng, WP; Su, J; Chen, SX; Song, HY; Aldalbahi, A; Zuo, XL; Song, SP; Shi, JY; Fan, CH
刊名: JOURNAL OF ELECTROANALYTICAL CHEMISTRY
出版日期: 2016
卷号: 781, 页码:339-344
关键词: Electrochemistry ; Portable ; Sensor ; Smartphone ; Electrical field
DOI: 10.1016/j.jelechem.2016.04.022
通讯作者: Song, SP ; Fan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai 201800, Peoples R China. ; Song, SP ; Fan, CH (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Bioimaging Ctr, Shanghai Synchrotron Radiat Facil, Shanghai 201800, Peoples R China.
文章类型: 期刊论文
英文摘要: We have developed a fast, highly sensitive and low-cost biosensing system for the detection of clenbuterol (CLB), using a homemade mobile electrochemical device with an electric field-driven acceleration strategy. This system consists of an embedded circuit in smartphone for signal processing and a screen-printed carbon electrode (SPCE) modified with multi-walled carbon nanotubes (MWNTs) and goat anti mouse-immunoglobulin G (IgG) sensing layer (MWNTs-I-layer). CLB monoclonal antibody was assembled through its binding to the surface confined antibody. Such modified electrodes were used for rapid and sensitive amperometric immunosensing detection of CLB. Horseradish peroxidase-coupled CLB (CLB-HRP) competed with free CLB in the samples to bind the monoclonal antibody. By using this mobile system, we could detect CLB ranging from 03 ng.mL(-1) to 100 ng.mL(-1) with the detection limit of 0.076 ng.mL(-1). The whole competitive-type detection process was finished within 6 min. We expect this device can meet the requirements for field detection of various food security-related species. (C) 2016 Elsevier B.V. All rights reserved.
收录类别: SCI
语种: 英语
WOS记录号: WOS:000390494200052
ISSN号: 1572-6657
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinap.ac.cn/handle/331007/26599
Appears in Collections:中科院上海应用物理研究所2011-2017年_期刊论文

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