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CAS OpenIR  > 中科院上海应用物理研究所2011-2017年  > 期刊论文
题名:
Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT
作者: Tan, H; Fu, Y; Wang, DD; Zhang, X; Xiao, TQ
刊名: NUCLEAR SCIENCE AND TECHNIQUES
出版日期: 2016
卷号: 27, 期号:5, 页码:-
关键词: SR-mu CT imaging ; 3D image processing ; Quantitative analysis ; 3D vasculature ; Angiogenesis
DOI: 10.1007/s41365-016-0121-7
通讯作者: Xiao, TQ (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Jiading Campus, Shanghai 201800, Peoples R China. ; Xiao, TQ (reprint author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China. ; Zhang, X (reprint author), Fudan Univ, Canc Hosp, Dept Radiol, Shanghai 200032, Peoples R China. ; Zhang, X (reprint author), Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China.
文章类型: 期刊论文
英文摘要: The micro-CT imaging of vasculature is a powerful tool for evaluation of angiogenesis, a prominent characteristic of hepatic fibrosis. The segment or bifurcation density, which is usually adopted to evaluate the degree of hepatic fibrosis, does not always work and may lead to incorrect assessment, especially when the three-dimensional vasculature obtained is imperfect in sample preparation or image collection. In this paper, we propose a new parameter to solve this problem. The experimental results demonstrate that the method is robust and reliable, and is practical for angiogenesis evaluation, despite of image data imperfections. This quantitative analysis method can be extended to investigate other kinds of diseases in which vasculature change is a key indicator.
收录类别: SCI
语种: 英语
WOS记录号: WOS:000388510700022
ISSN号: 1001-8042
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinap.ac.cn/handle/331007/26610
Appears in Collections:中科院上海应用物理研究所2011-2017年_期刊论文

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Recommended Citation:
Tan, H,Fu, Y,Wang, DD,et al. Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT[J]. NUCLEAR SCIENCE AND TECHNIQUES,2016-01-01,27(5):-.
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