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| Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT | |
| Tan, H; Fu, Y; Wang, DD; Zhang, X; Xiao, TQ; Xiao, TQ (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Jiading Campus, Shanghai 201800, Peoples R China.; Xiao, TQ (reprint author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Canc Hosp, Dept Radiol, Shanghai 200032, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China. | |
| 2016 | |
| Source Publication | NUCLEAR SCIENCE AND TECHNIQUES
 |
| ISSN | 1001-8042 |
| Volume | 27Issue:5Pages:- |
| Subtype | 期刊论文 |
| Abstract | The micro-CT imaging of vasculature is a powerful tool for evaluation of angiogenesis, a prominent characteristic of hepatic fibrosis. The segment or bifurcation density, which is usually adopted to evaluate the degree of hepatic fibrosis, does not always work and may lead to incorrect assessment, especially when the three-dimensional vasculature obtained is imperfect in sample preparation or image collection. In this paper, we propose a new parameter to solve this problem. The experimental results demonstrate that the method is robust and reliable, and is practical for angiogenesis evaluation, despite of image data imperfections. This quantitative analysis method can be extended to investigate other kinds of diseases in which vasculature change is a key indicator. |
| Keyword | Sr-mu Ct Imaging 3d Image Processing Quantitative Analysis 3d Vasculature Angiogenesis |
| DOI | 10.1007/s41365-016-0121-7 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000388510700022 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/26610 |
| Collection | 中科院上海应用物理研究所2011-2020年 |
| Corresponding Author | Xiao, TQ (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Jiading Campus, Shanghai 201800, Peoples R China.; Xiao, TQ (reprint author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Canc Hosp, Dept Radiol, Shanghai 200032, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China. |
| Recommended Citation GB/T 7714 | Tan, H,Fu, Y,Wang, DD,et al. Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT[J]. NUCLEAR SCIENCE AND TECHNIQUES,2016,27(5):-. |
| APA | Tan, H.,Fu, Y.,Wang, DD.,Zhang, X.,Xiao, TQ.,...&Zhang, X .(2016).Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT.NUCLEAR SCIENCE AND TECHNIQUES,27(5),-. |
| MLA | Tan, H,et al."Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT".NUCLEAR SCIENCE AND TECHNIQUES 27.5(2016):-. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Quantitative analysi（3615KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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