Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT
Tan, H; Fu, Y; Wang, DD; Zhang, X; Xiao, TQ; Xiao, TQ (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Jiading Campus, Shanghai 201800, Peoples R China.; Xiao, TQ (reprint author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Canc Hosp, Dept Radiol, Shanghai 200032, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China.
2016
发表期刊NUCLEAR SCIENCE AND TECHNIQUES
ISSN1001-8042
卷号27期号:5页码:-
文章类型期刊论文
摘要The micro-CT imaging of vasculature is a powerful tool for evaluation of angiogenesis, a prominent characteristic of hepatic fibrosis. The segment or bifurcation density, which is usually adopted to evaluate the degree of hepatic fibrosis, does not always work and may lead to incorrect assessment, especially when the three-dimensional vasculature obtained is imperfect in sample preparation or image collection. In this paper, we propose a new parameter to solve this problem. The experimental results demonstrate that the method is robust and reliable, and is practical for angiogenesis evaluation, despite of image data imperfections. This quantitative analysis method can be extended to investigate other kinds of diseases in which vasculature change is a key indicator.
关键词Sr-mu Ct Imaging 3d Image Processing Quantitative Analysis 3d Vasculature Angiogenesis
DOI10.1007/s41365-016-0121-7
收录类别SCI
语种英语
WOS记录号WOS:000388510700022
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/26610
专题中科院上海应用物理研究所2011-2018年
通讯作者Xiao, TQ (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Jiading Campus, Shanghai 201800, Peoples R China.; Xiao, TQ (reprint author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Canc Hosp, Dept Radiol, Shanghai 200032, Peoples R China.; Zhang, X (reprint author), Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China.
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Tan, H,Fu, Y,Wang, DD,et al. Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT[J]. NUCLEAR SCIENCE AND TECHNIQUES,2016,27(5):-.
APA Tan, H.,Fu, Y.,Wang, DD.,Zhang, X.,Xiao, TQ.,...&Zhang, X .(2016).Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT.NUCLEAR SCIENCE AND TECHNIQUES,27(5),-.
MLA Tan, H,et al."Quantitative analysis of 3D vasculature for evaluation of angiogenesis in liver fibrosis with SR-mu CT".NUCLEAR SCIENCE AND TECHNIQUES 27.5(2016):-.
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