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题名: Strong Hydrophobic Interaction Between Graphene Oxide and Supported Lipid Bilayers Revealed by AFM
作者: Hu, XY; Lei, HZ; Zhang, XQ; Zhang, Y
刊名: MICROSCOPY RESEARCH AND TECHNIQUE
出版日期: 2016
卷号: 79, 期号:8, 页码:721-726
关键词: graphene oxide (GO) ; supported lipid bilayers (SLBs) ; hydrophobic interaction ; atomic force microscope (AFM)
DOI: 10.1002/jemt.22690
通讯作者: Zhang, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
文章类型: 期刊论文
英文摘要: Understanding the interaction between graphene oxide (GO) and lipid membranes is of great importance for its various applications in biotechnology. Here, we investigated the interaction between GO and charged supported lipid bilayers (SLBs) by in situ atomic force microscope (AFM) imaging. It was found that GO could peel off a single layer of positively charged SLBs and deposited on the hydrophobic part of the remaining sublayer. Then free lipid molecules would assemble on GO surface and formed 1.5 bilayers in a lipid-GO-lipid manner. For negatively charged lipid bilayers, however, GO deposited to the SLBs only when its concentration was very high. These results indicate that, in addition to electrostatic interaction, the hydrophobic interaction plays an important role when GO sheets deposit onto the charged lipid bilayers, and should be helpful to understand possible cytotoxicity and antibiosis of graphene-related nanomaterials. (C) 2016 Wiley Periodicals, Inc.
收录类别: SCI
语种: 英语
WOS记录号: WOS:000380144800007
ISSN号: 1059-910X
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinap.ac.cn/handle/331007/26632
Appears in Collections:中科院上海应用物理研究所2011-2017年_期刊论文

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