CAS OpenIR  > 中科院上海应用物理研究所2011-2018年
Terahertz identification and quantification of neurotransmitter and neurotrophy mixture
Peng, Y; Yuan, XR; Zou, X; Chen, WQ; Huang, H; Zhao, HW; Song, B; Chen, L; Zhu, YM; Chen, L (reprint author), Fudan Univ, Hua Shan Hosp, Shanghai 200040, Peoples R China.
2016
Source PublicationBIOMEDICAL OPTICS EXPRESS
ISSN2156-7085
Volume7Issue:11Pages:4472-4479
Subtype期刊论文
AbstractTerahertz spectroscopy has been widely used for investigating the fingerprint spectrum of different substances. For cancerous tissues, the greatest difficulty is the absorption peaks of various substances contained in tissues overlap with each other, which are hard to identify and quantitative analyze. As a result, it is very hard to measure the presence of cancer cell and then to diagnose accurately. In this paper, we select three typical neurotransmitters (gamma-aminobutyric acid, L-glutamic acid, dopamine hydrochloride) and two typical metabolites (inositol and creatine) in neurons to measure their terahertz spectra with different mixture ratios. By choosing characteristic absorption peaks, removing baseline and using the least square method, we can identify the components and proportions of each mixture, where the goodness of fit to practical situation is up to 94%. These results provide important evidences for identifying nerve substances and obtaining exact quantitative analysis. (C) 2016 Optical Society of America
DOI10.1364/BOE.7.004472
Indexed BySCI
Language英语
WOS IDWOS:000387557600010
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/26650
Collection中科院上海应用物理研究所2011-2018年
Corresponding AuthorChen, L (reprint author), Fudan Univ, Hua Shan Hosp, Shanghai 200040, Peoples R China.
Recommended Citation
GB/T 7714
Peng, Y,Yuan, XR,Zou, X,et al. Terahertz identification and quantification of neurotransmitter and neurotrophy mixture[J]. BIOMEDICAL OPTICS EXPRESS,2016,7(11):4472-4479.
APA Peng, Y.,Yuan, XR.,Zou, X.,Chen, WQ.,Huang, H.,...&Chen, L .(2016).Terahertz identification and quantification of neurotransmitter and neurotrophy mixture.BIOMEDICAL OPTICS EXPRESS,7(11),4472-4479.
MLA Peng, Y,et al."Terahertz identification and quantification of neurotransmitter and neurotrophy mixture".BIOMEDICAL OPTICS EXPRESS 7.11(2016):4472-4479.
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