Terahertz identification and quantification of neurotransmitter and neurotrophy mixture
Peng, Y; Yuan, XR; Zou, X; Chen, WQ; Huang, H; Zhao, HW; Song, B; Chen, L; Zhu, YM; Chen, L (reprint author), Fudan Univ, Hua Shan Hosp, Shanghai 200040, Peoples R China.
2016
发表期刊BIOMEDICAL OPTICS EXPRESS
ISSN2156-7085
卷号7期号:11页码:4472-4479
文章类型期刊论文
摘要Terahertz spectroscopy has been widely used for investigating the fingerprint spectrum of different substances. For cancerous tissues, the greatest difficulty is the absorption peaks of various substances contained in tissues overlap with each other, which are hard to identify and quantitative analyze. As a result, it is very hard to measure the presence of cancer cell and then to diagnose accurately. In this paper, we select three typical neurotransmitters (gamma-aminobutyric acid, L-glutamic acid, dopamine hydrochloride) and two typical metabolites (inositol and creatine) in neurons to measure their terahertz spectra with different mixture ratios. By choosing characteristic absorption peaks, removing baseline and using the least square method, we can identify the components and proportions of each mixture, where the goodness of fit to practical situation is up to 94%. These results provide important evidences for identifying nerve substances and obtaining exact quantitative analysis. (C) 2016 Optical Society of America
DOI10.1364/BOE.7.004472
收录类别SCI
语种英语
WOS记录号WOS:000387557600010
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/26650
专题中科院上海应用物理研究所2011-2018年
通讯作者Chen, L (reprint author), Fudan Univ, Hua Shan Hosp, Shanghai 200040, Peoples R China.
推荐引用方式
GB/T 7714
Peng, Y,Yuan, XR,Zou, X,et al. Terahertz identification and quantification of neurotransmitter and neurotrophy mixture[J]. BIOMEDICAL OPTICS EXPRESS,2016,7(11):4472-4479.
APA Peng, Y.,Yuan, XR.,Zou, X.,Chen, WQ.,Huang, H.,...&Chen, L .(2016).Terahertz identification and quantification of neurotransmitter and neurotrophy mixture.BIOMEDICAL OPTICS EXPRESS,7(11),4472-4479.
MLA Peng, Y,et al."Terahertz identification and quantification of neurotransmitter and neurotrophy mixture".BIOMEDICAL OPTICS EXPRESS 7.11(2016):4472-4479.
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