CAS OpenIR  > 中科院上海应用物理研究所2011-2018年
Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels
Wang, JB; Chao, J; Liu, HJ; Su, S; Wang, LH; Huang, W; Willner, I; Fan, CH
2017
Source PublicationANGEWANDTE CHEMIE-INTERNATIONAL EDITION
ISSN1433-7851
Volume56Issue:8Pages:2171-2175
Subtype期刊论文
AbstractDNA hydrogels hold great potential for biological and biomedical applications owing to their programmable nature and macroscopic sizes. However, most previous studies involve spontaneous and homogenous gelation procedures in solution, which often lack precise control. A clamped hybridization chain reaction (C-HCR)-based strategy has been developed to guide DNA self-assembly to form macroscopic hydrogels. Analogous to catalysts in chemical synthesis or seeds in crystal growth, we introduced DNA initiators to induce the gelation process, including crosslinked self-assembly and clamped hybridization in three dimensions with spatial and temporal control. The formed hydrogels show superior mechanical properties. The use of printed, surface-confined DNA initiators was also demonstrated for fabricating 2D hydrogel patterns without relying on external confinements. This simple method can be used to construct DNA hydrogels with defined geometry, composition, and order for various bioapplications.
KeywordDna Hydrogels Dna Nanotechnology Nucleic Acid Hybridization Self-assembly Sol-gel Process
DOI10.1002/anie.201610125
Indexed BySCI
Language英语
WOS IDWOS:000397323300038
Citation statistics
Cited Times:34[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/27274
Collection中科院上海应用物理研究所2011-2018年
Recommended Citation
GB/T 7714
Wang, JB,Chao, J,Liu, HJ,et al. Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2017,56(8):2171-2175.
APA Wang, JB.,Chao, J.,Liu, HJ.,Su, S.,Wang, LH.,...&Fan, CH.(2017).Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,56(8),2171-2175.
MLA Wang, JB,et al."Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 56.8(2017):2171-2175.
Files in This Item: Download All
File Name/Size DocType Version Access License
Clamped Hybridizatio(2301KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, JB]'s Articles
[Chao, J]'s Articles
[Liu, HJ]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, JB]'s Articles
[Chao, J]'s Articles
[Liu, HJ]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, JB]'s Articles
[Chao, J]'s Articles
[Liu, HJ]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.