Effects of sintering temperature on surface morphology/microstructure, in vitro degradability, mineralization and osteoblast response to magnesium phosphate as biomedical material
Wang, ZW; Ma, YH; Wei, J; Chen, X; Cao, LH; Weng, WZ; Li, Q; Guo, H; Su, JC
2017
发表期刊SCIENTIFIC REPORTS
ISSN2045-2322
卷号7页码:-
文章类型期刊论文
摘要Magnesium phosphate (MP) was fabricated using a chemical precipitation method, and the biological performances of MP sintered at different temperatures as a biomedical material was investigated. The results indicated that the densification and crystallinity of MP increased as the sintering temperature increased. As the sintering temperature increased, the degradability of MP in PBS decreased, and the mineralization ability in SBF significantly increased. In addition, the MP sintered at 800 degrees C (MP8) possessed the lowest degradability and highest mineralization ability. Moreover, the positive response of MG63 cells to MP significantly increased as the sintering temperature increased, and MP8 significantly promoted the cell spreading, proliferation, differentiation and expressions of osteogenic differentiation-related genes. Faster degradation of MP0 resulted in higher pH environments and ion concentrations, which led to negative responses to osteoblasts. However, the appropriate degradation of MP8 resulted in suitable pH environments and ion concentrations, which led to positive responses to osteoblasts. This study demonstrated that the sintering temperature substantially affected the surface morphology/microstructure, degradability and mineralization, and osteoblasts response to magnesium phosphate.
DOI10.1038/s41598-017-00905-2
收录类别SCI
语种英语
WOS记录号WOS:000398824300040
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/27306
专题中科院上海应用物理研究所2011-2018年
推荐引用方式
GB/T 7714
Wang, ZW,Ma, YH,Wei, J,et al. Effects of sintering temperature on surface morphology/microstructure, in vitro degradability, mineralization and osteoblast response to magnesium phosphate as biomedical material[J]. SCIENTIFIC REPORTS,2017,7:-.
APA Wang, ZW.,Ma, YH.,Wei, J.,Chen, X.,Cao, LH.,...&Su, JC.(2017).Effects of sintering temperature on surface morphology/microstructure, in vitro degradability, mineralization and osteoblast response to magnesium phosphate as biomedical material.SCIENTIFIC REPORTS,7,-.
MLA Wang, ZW,et al."Effects of sintering temperature on surface morphology/microstructure, in vitro degradability, mineralization and osteoblast response to magnesium phosphate as biomedical material".SCIENTIFIC REPORTS 7(2017):-.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Effects of sintering(3167KB)期刊论文作者接受稿开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang, ZW]的文章
[Ma, YH]的文章
[Wei, J]的文章
百度学术
百度学术中相似的文章
[Wang, ZW]的文章
[Ma, YH]的文章
[Wei, J]的文章
必应学术
必应学术中相似的文章
[Wang, ZW]的文章
[Ma, YH]的文章
[Wei, J]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。