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Fluorescent biosensors enabled by graphene and graphene oxide
Zhang, H; Zhang, HL; Aldalbahi, A; Zuo, XL; Fan, CH; Mi, XQ
2017
Source PublicationBIOSENSORS & BIOELECTRONICS
ISSN0956-5663
Volume89Pages:96-106
Subtype期刊论文
AbstractDuring the past few years, graphene and graphene oxide (GO) have attracted numerous attentions for the potential applications in various fields from energy technology, biosensing to biomedical diagnosis and therapy due to their various functionalization, high volume surface ratio, unique physical and electrical properties. Among which, graphene and graphene oxide based fluorescent biosensors enabled by their fluorescence-quenching properties have attracted great interests. The fluorescence of fluorophore or dye labeled on probes (such as molecular beacon, aptamer, DNAzymes and so on) was quenched after adsorbed on to the surface of graphene. While in the present of the targets, due to the strong interactions between probes and targets, the probes were detached from the surface of graphene, generating dramatic fluorescence, which could be used as signals for detection of the targets. This strategy was simple and economy, together with great programmable abilities of probes; we could realize detection of different kinds of species. In this review, we first briefly introduced the history of graphene and graphene oxide, and then summarized the fluorescent biosensors enabled by graphene and GO, with a detailed account of the design mechanism and comparison with other nanomaterials (e.g. carbon nanotubes and gold nanoparticles). Following that, different sensing platforms for detection of DNAs, ions, biomolecules and pathogens or cells as well as the cytotoxicity issue of graphene and GO based in vivo biosensing were further discussed. We hope that this review would do some help to researchers who are interested in graphene related biosening research work. (C) 2016 Elsevier B.V. All rights reserved.
KeywordGraphene Graphene Oxide Biosensor Fluorescent Detection
DOI10.1016/j.bios.2016.07.030
Indexed BySCI
Language英语
WOS IDWOS:000391077000008
Citation statistics
Cited Times:60[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/27329
Collection中科院上海应用物理研究所2011-2018年
Recommended Citation
GB/T 7714
Zhang, H,Zhang, HL,Aldalbahi, A,et al. Fluorescent biosensors enabled by graphene and graphene oxide[J]. BIOSENSORS & BIOELECTRONICS,2017,89:96-106.
APA Zhang, H,Zhang, HL,Aldalbahi, A,Zuo, XL,Fan, CH,&Mi, XQ.(2017).Fluorescent biosensors enabled by graphene and graphene oxide.BIOSENSORS & BIOELECTRONICS,89,96-106.
MLA Zhang, H,et al."Fluorescent biosensors enabled by graphene and graphene oxide".BIOSENSORS & BIOELECTRONICS 89(2017):96-106.
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