Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection
Su, J; Wang, DF; Norbel, L; Shen, JL; Zhao, ZH; Dou, YZ; Peng, TH; Shi, JY; Mathur, S; Fan, CH; Song, SP
2017
发表期刊ANALYTICAL CHEMISTRY
ISSN0003-2700
卷号89期号:4页码:2531-2538
文章类型期刊论文
摘要Uniform silver-containing metal nanostructures with strong and stable surface enhanced Raman scattering (SERS) signals hold great promise for developing ultrasensitive probes for biodetection. Nevertheless, the direct synthesis of such ready-to-use nanoprobes remains extremely challenging. Herein we report a DNA-mediated gold silver nanomushroom with interior nanogaps directly synthesized and used for multiplex and simultaneous SERS detection of various DNA and RNA targets. The DNA involved in the nanostructures can act as hot only gap DNA (mediated DNA) but also probe DNA (hybridized DNA), and DNA's involvement enables the nanostructures to have the inherent ability to recognize DNA and RNA targets. Importantly, we were the first to establish a new method for the generation of multicolor SERS probes using two different strategies. First Raman-labeled alkanethiol probe DNA was assembled on gold nanoparticles, and second, thiol-containing Raman reporters were coassembled with the probe DNA. The ready-to-use probes also give great potential to develop ultrasensitive detection methods for various biological molecules.
DOI10.1021/acs.analchem.6b04729
收录类别SCI
语种英语
WOS记录号WOS:000394724700050
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/27389
专题中科院上海应用物理研究所2011-2018年
推荐引用方式
GB/T 7714
Su, J,Wang, DF,Norbel, L,et al. Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection[J]. ANALYTICAL CHEMISTRY,2017,89(4):2531-2538.
APA Su, J.,Wang, DF.,Norbel, L.,Shen, JL.,Zhao, ZH.,...&Song, SP.(2017).Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection.ANALYTICAL CHEMISTRY,89(4),2531-2538.
MLA Su, J,et al."Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection".ANALYTICAL CHEMISTRY 89.4(2017):2531-2538.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Multicolor Gold Silv(6018KB)期刊论文作者接受稿开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Su, J]的文章
[Wang, DF]的文章
[Norbel, L]的文章
百度学术
百度学术中相似的文章
[Su, J]的文章
[Wang, DF]的文章
[Norbel, L]的文章
必应学术
必应学术中相似的文章
[Su, J]的文章
[Wang, DF]的文章
[Norbel, L]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。