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| Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study | |
| Li, HX; Liu, YC; Tang, RZ; Zhang, P; Ma, LK; Wei, CY; Wang, WF | |
| 2017 | |
| Source Publication | ACTA PHYSICO-CHIMICA SINICA
 |
| ISSN | 1000-6818 |
| Volume | 33Issue:5Pages:1051-1056 |
| Subtype | 期刊论文 |
| Abstract | The reactions of triplet-state difloxacin (DFX) with various amino acids and deoxyguanylic acid in aqueous media were studied using laser flash photolysis. Tryptophan, tyrosine, cysteine, and 2'-deoxyguanosine5'-monophosphate (dGMP) were found to completely quench the triplet state of DFX in aqueous solution, the corresponding second-order rate constants being 1.97 x 10(8), 1.48 x 10(8), 1.72 x 10(8), and 6.92 x 10(7) dm(3).mol(-l).s(-1) . The quenching mechanism involves electron transfer to the photoexcited triplet state of DFX from the tryptophan, tyrosine, cysteine, and dGMP moieties, followed by fast protonation of the resulting DFX anion radical. |
| Keyword | Laser Flash Photolysis Difloxacin Triplet State Amino Acid |
| DOI | 10.3866/PKU.WHXB201702201 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000401878800027 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/27431 |
| Collection | 中科院上海应用物理研究所2011-2018年 |
| Recommended Citation GB/T 7714 | Li, HX,Liu, YC,Tang, RZ,et al. Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study[J]. ACTA PHYSICO-CHIMICA SINICA,2017,33(5):1051-1056. |
| APA | Li, HX.,Liu, YC.,Tang, RZ.,Zhang, P.,Ma, LK.,...&Wang, WF.(2017).Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study.ACTA PHYSICO-CHIMICA SINICA,33(5),1051-1056. |
| MLA | Li, HX,et al."Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study".ACTA PHYSICO-CHIMICA SINICA 33.5(2017):1051-1056. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Reactions of Triplet（1063KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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