CAS OpenIR  > 中科院上海应用物理研究所2011-2018年
Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study
Li, HX; Liu, YC; Tang, RZ; Zhang, P; Ma, LK; Wei, CY; Wang, WF
2017
Source PublicationACTA PHYSICO-CHIMICA SINICA
ISSN1000-6818
Volume33Issue:5Pages:1051-1056
Subtype期刊论文
AbstractThe reactions of triplet-state difloxacin (DFX) with various amino acids and deoxyguanylic acid in aqueous media were studied using laser flash photolysis. Tryptophan, tyrosine, cysteine, and 2'-deoxyguanosine5'-monophosphate (dGMP) were found to completely quench the triplet state of DFX in aqueous solution, the corresponding second-order rate constants being 1.97 x 10(8), 1.48 x 10(8), 1.72 x 10(8), and 6.92 x 10(7) dm(3).mol(-l).s(-1) . The quenching mechanism involves electron transfer to the photoexcited triplet state of DFX from the tryptophan, tyrosine, cysteine, and dGMP moieties, followed by fast protonation of the resulting DFX anion radical.
KeywordLaser Flash Photolysis Difloxacin Triplet State Amino Acid
DOI10.3866/PKU.WHXB201702201
Indexed BySCI
Language英语
WOS IDWOS:000401878800027
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sinap.ac.cn/handle/331007/27431
Collection中科院上海应用物理研究所2011-2018年
Recommended Citation
GB/T 7714
Li, HX,Liu, YC,Tang, RZ,et al. Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study[J]. ACTA PHYSICO-CHIMICA SINICA,2017,33(5):1051-1056.
APA Li, HX.,Liu, YC.,Tang, RZ.,Zhang, P.,Ma, LK.,...&Wang, WF.(2017).Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study.ACTA PHYSICO-CHIMICA SINICA,33(5),1051-1056.
MLA Li, HX,et al."Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study".ACTA PHYSICO-CHIMICA SINICA 33.5(2017):1051-1056.
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