Self-Assembly of Amyloid-Like Peptides at Interfaces Investigated by Atomic Force Microscopy
Lei, HZ; Zhang, XQ; Hu, J; Zhang, Y
2017
发表期刊SCIENCE OF ADVANCED MATERIALS
ISSN1947-2935
卷号9期号:1页码:65-76
文章类型期刊论文
摘要In the past few years, numerous researches have focused on the self-assembly of amyloid peptides and proteins. Especially, the self-assembly of peptides and proteins at interfaces has attracted much attention, on account of the potential applications as well as understanding mechanism of some neurodegenerative diseases. In this review, we centered topic on recent progress of the self-assembly of amyloid-like peptides at interfaces, which was mainly carried out in our group by employing atomic force microscopy (AFM). In the first part of the review, we introduced how the amyloid peptides assembled at the solid substrate/water interface. And nanoscale control of the assembly of the peptides by AFM has also been introduced. In the second part of this review, we focused on how the amyloid-like peptides assembled at air/solid interface, in which diffusion and self-assembly of peptides occurred with the help of a water nanofilm confined from ambient environment onto the solid surface. These results indicate that interfaces play an important role in peptide assembly, and also prove that AFM is one of the powerful instruments in studying peptide self-assembly.
关键词Peptide Self-assembly Afm Interface
DOI10.1166/sam.2017.2737
收录类别SCI
语种英语
WOS记录号WOS:000396469000013
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/27437
专题中科院上海应用物理研究所2011-2018年
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Lei, HZ,Zhang, XQ,Hu, J,et al. Self-Assembly of Amyloid-Like Peptides at Interfaces Investigated by Atomic Force Microscopy[J]. SCIENCE OF ADVANCED MATERIALS,2017,9(1):65-76.
APA Lei, HZ,Zhang, XQ,Hu, J,&Zhang, Y.(2017).Self-Assembly of Amyloid-Like Peptides at Interfaces Investigated by Atomic Force Microscopy.SCIENCE OF ADVANCED MATERIALS,9(1),65-76.
MLA Lei, HZ,et al."Self-Assembly of Amyloid-Like Peptides at Interfaces Investigated by Atomic Force Microscopy".SCIENCE OF ADVANCED MATERIALS 9.1(2017):65-76.
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