Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging
Zhu, Y; Zhang, JC; Li, AG; Zhang, YQ; Fan, CH
2017
发表期刊CURRENT OPINION IN CHEMICAL BIOLOGY
ISSN1367-5931
卷号39期号:-页码:11-16
文章类型期刊论文
摘要Microscopic imaging provides a straightforward approach to deepen our understanding of cellular events. While the resolution of optical microscopes is generally limited to 200-300 nm due to the diffraction limit, there has been ever growing interest in studying cells at the sub-100 nm regime. By exploiting the short wavelength, long penetration depth and elemental specificity of X-rays, synchrotron-based X-ray microscopy (XRM) has demonstrated its power in exploring the structure and function of cells at the nanometer resolution. Here we summarize recent advances in using XRM for imaging ultrastructure of organelles and specific biomolecular locations in cells, and provide a perspective on potentials and applications of XRM.
关键词Fluorescence Microscopy Diffraction Microscopy Tio2 Nanoparticles Quantum Dots Metal-ions Nanoscale Cytotoxicity Tomography Breaking Whole
DOI10.1016/j.cbpa.2017.04.016
关键词[WOS]FLUORESCENCE MICROSCOPY ; DIFFRACTION MICROSCOPY ; TIO2 NANOPARTICLES ; QUANTUM DOTS ; METAL-IONS ; NANOSCALE ; CYTOTOXICITY ; TOMOGRAPHY ; BREAKING ; WHOLE
收录类别SCI
语种英语
WOS记录号WOS:000411419500004
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/28843
专题中科院上海应用物理研究所2011-2018年
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Zhu, Y,Zhang, JC,Li, AG,et al. Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging[J]. CURRENT OPINION IN CHEMICAL BIOLOGY,2017,39(-):11-16.
APA Zhu, Y,Zhang, JC,Li, AG,Zhang, YQ,&Fan, CH.(2017).Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging.CURRENT OPINION IN CHEMICAL BIOLOGY,39(-),11-16.
MLA Zhu, Y,et al."Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging".CURRENT OPINION IN CHEMICAL BIOLOGY 39.-(2017):11-16.
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