Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging

doi:10.1016/j.cbpa.2017.04.016

CAS OpenIR > 中科院上海应用物理研究所2011-2018年

	Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging
	Zhu, Y; Zhang, JC; Li, AG; Zhang, YQ; Fan, CH
	2017
Source Publication	CURRENT OPINION IN CHEMICAL BIOLOGY
ISSN	1367-5931
Volume	39 Issue:-Pages:11-16
Subtype	期刊论文
Abstract	Microscopic imaging provides a straightforward approach to deepen our understanding of cellular events. While the resolution of optical microscopes is generally limited to 200-300 nm due to the diffraction limit, there has been ever growing interest in studying cells at the sub-100 nm regime. By exploiting the short wavelength, long penetration depth and elemental specificity of X-rays, synchrotron-based X-ray microscopy (XRM) has demonstrated its power in exploring the structure and function of cells at the nanometer resolution. Here we summarize recent advances in using XRM for imaging ultrastructure of organelles and specific biomolecular locations in cells, and provide a perspective on potentials and applications of XRM.
Keyword	Fluorescence Microscopy Diffraction Microscopy Tio2 Nanoparticles Quantum Dots Metal-ions Nanoscale Cytotoxicity Tomography Breaking Whole
DOI	10.1016/j.cbpa.2017.04.016
WOS Keyword	FLUORESCENCE MICROSCOPY ; DIFFRACTION MICROSCOPY ; TIO2 NANOPARTICLES ; QUANTUM DOTS ; METAL-IONS ; NANOSCALE ; CYTOTOXICITY ; TOMOGRAPHY ; BREAKING ; WHOLE
Indexed By	SCI
Language	英语
WOS ID	WOS:000411419500004
Citation statistics	Cited Times:5[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.sinap.ac.cn/handle/331007/28843
Collection	中科院上海应用物理研究所2011-2018年
Recommended Citation GB/T 7714	Zhu, Y,Zhang, JC,Li, AG,et al. Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging[J]. CURRENT OPINION IN CHEMICAL BIOLOGY,2017,39(-):11-16.
APA	Zhu, Y,Zhang, JC,Li, AG,Zhang, YQ,&Fan, CH.(2017).Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging.CURRENT OPINION IN CHEMICAL BIOLOGY,39(-),11-16.
MLA	Zhu, Y,et al."Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging".CURRENT OPINION IN CHEMICAL BIOLOGY 39.-(2017):11-16.

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