Knowledge Management System Of Shanghai Institute of Applied Physics, CAS
| Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging | |
| Zhu, Y; Zhang, JC; Li, AG; Zhang, YQ; Fan, CH | |
| 2017 | |
| Source Publication | CURRENT OPINION IN CHEMICAL BIOLOGY
 |
| ISSN | 1367-5931 |
| Volume | 39Issue:-Pages:11-16 |
| Subtype | 期刊论文 |
| Abstract | Microscopic imaging provides a straightforward approach to deepen our understanding of cellular events. While the resolution of optical microscopes is generally limited to 200-300 nm due to the diffraction limit, there has been ever growing interest in studying cells at the sub-100 nm regime. By exploiting the short wavelength, long penetration depth and elemental specificity of X-rays, synchrotron-based X-ray microscopy (XRM) has demonstrated its power in exploring the structure and function of cells at the nanometer resolution. Here we summarize recent advances in using XRM for imaging ultrastructure of organelles and specific biomolecular locations in cells, and provide a perspective on potentials and applications of XRM. |
| Keyword | Fluorescence Microscopy Diffraction Microscopy Tio2 Nanoparticles Quantum Dots Metal-ions Nanoscale Cytotoxicity Tomography Breaking Whole |
| DOI | 10.1016/j.cbpa.2017.04.016 |
| Indexed By | SCI |
| WOS Keyword | FLUORESCENCE MICROSCOPY ; DIFFRACTION MICROSCOPY ; TIO2 NANOPARTICLES ; QUANTUM DOTS ; METAL-IONS ; NANOSCALE ; CYTOTOXICITY ; TOMOGRAPHY ; BREAKING ; WHOLE |
| Language | 英语 |
| WOS ID | WOS:000411419500004 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/28843 |
| Collection | 中科院上海应用物理研究所2011-2020年 |
| Recommended Citation GB/T 7714 | Zhu, Y,Zhang, JC,Li, AG,et al. Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging[J]. CURRENT OPINION IN CHEMICAL BIOLOGY,2017,39(-):11-16. |
| APA | Zhu, Y,Zhang, JC,Li, AG,Zhang, YQ,&Fan, CH.(2017).Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging.CURRENT OPINION IN CHEMICAL BIOLOGY,39(-),11-16. |
| MLA | Zhu, Y,et al."Synchrotron-based X-ray microscopy for sub-100 nm resolution cell imaging".CURRENT OPINION IN CHEMICAL BIOLOGY 39.-(2017):11-16. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Synchrotron-based X-（1151KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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