CAS OpenIR  > 中科院上海应用物理研究所2011-2020年
Framework-Nucleic-Acid-Enabled Biosensor Development
Yang, F; Li, Q; Wang, LH; Zhang, GJ; Fan, CH
Source PublicationACS SENSORS
AbstractNucleic acids have been actively exploited to develop various exquisite nanostructures due to their unparalleled programmability. Especially, framework nucleic acids (FNAs) with tailorable functionality and precise addressability hold great promise for biomedical applications. In this review, we summarize recent progress of FNA-enabled biosensing in homogeneous solutions, on heterogeneous surfaces, and inside cells. We describe the strategies to translate the structural order and rigidity of FNAs to interfacial engineering with high controllability, and approaches to realize multiplexing for highly parallel in vitro detection. We also envision the marriage of the currently available FNA tool sets with other emerging technologies to develop a new generation of biosensors for precision diagnosis and bioimaging.
KeywordTetrahedral Dna Nanostructure Rolling Circle Amplification Mediated Strand Displacement Chain-reaction Amplification Highly Sensitive Detection Prostate-specific Antigen Solid-state Nanopores Living Cells Electrochemical Detection Drug-delivery
Indexed BySCI
WOS IDWOS:000433635300003
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Document Type期刊论文
Affiliation1.Yang, F
2.Li, Q
3.Wang, LH
4.Zhang, GJ
5.Fan, CH
Recommended Citation
GB/T 7714
Yang, F,Li, Q,Wang, LH,et al. Framework-Nucleic-Acid-Enabled Biosensor Development[J]. ACS SENSORS,2018,3(5):903-919.
APA Yang, F,Li, Q,Wang, LH,Zhang, GJ,&Fan, CH.(2018).Framework-Nucleic-Acid-Enabled Biosensor Development.ACS SENSORS,3(5),903-919.
MLA Yang, F,et al."Framework-Nucleic-Acid-Enabled Biosensor Development".ACS SENSORS 3.5(2018):903-919.
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