Framework-Nucleic-Acid-Enabled Biosensor Development
Yang, F; Li, Q; Wang, LH; Zhang, GJ; Fan, CH
2018
发表期刊ACS SENSORS
ISSN2379-3694
卷号3期号:5页码:903-919
文章类型期刊论文
摘要Nucleic acids have been actively exploited to develop various exquisite nanostructures due to their unparalleled programmability. Especially, framework nucleic acids (FNAs) with tailorable functionality and precise addressability hold great promise for biomedical applications. In this review, we summarize recent progress of FNA-enabled biosensing in homogeneous solutions, on heterogeneous surfaces, and inside cells. We describe the strategies to translate the structural order and rigidity of FNAs to interfacial engineering with high controllability, and approaches to realize multiplexing for highly parallel in vitro detection. We also envision the marriage of the currently available FNA tool sets with other emerging technologies to develop a new generation of biosensors for precision diagnosis and bioimaging.
关键词Tetrahedral Dna Nanostructure Rolling Circle Amplification Mediated Strand Displacement Chain-reaction Amplification Highly Sensitive Detection Prostate-specific Antigen Solid-state Nanopores Living Cells Electrochemical Detection Drug-delivery
DOI10.1021/acssensors.8b00257
收录类别SCI
语种英语
WOS记录号WOS:000433635300003
引用统计
文献类型期刊论文
条目标识符http://ir.sinap.ac.cn/handle/331007/29025
专题中科院上海应用物理研究所2011-2018年
作者单位1.Yang, F
2.Li, Q
3.Wang, LH
4.Zhang, GJ
5.Fan, CH
推荐引用方式
GB/T 7714
Yang, F,Li, Q,Wang, LH,et al. Framework-Nucleic-Acid-Enabled Biosensor Development[J]. ACS SENSORS,2018,3(5):903-919.
APA Yang, F,Li, Q,Wang, LH,Zhang, GJ,&Fan, CH.(2018).Framework-Nucleic-Acid-Enabled Biosensor Development.ACS SENSORS,3(5),903-919.
MLA Yang, F,et al."Framework-Nucleic-Acid-Enabled Biosensor Development".ACS SENSORS 3.5(2018):903-919.
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