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| Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric | |
| Li, R; Cai, XM; Ye, Y; Wu, GZ | |
| 2018 | |
| Source Publication | JOURNAL OF APPLIED POLYMER SCIENCE
 |
| ISSN | 0021-8995 |
| Volume | 135Issue:9Pages:- |
| Subtype | 期刊论文 |
| Abstract | The sulfonated polypropylene non-woven fabric (PPNWF) was successfully fabricated via gamma-ray simultaneous radiationinduced graft polymerization of acrylic acid (AA)/sodium styrenesulfonate (NaSS) and acrylamide (AAm)/NaSS. The existence of graft chains in both PP-g-P(AA-co-NaSS) and PP-g-P(AAm-co-NaSS) was proved by attenuated total reflection Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. Water contact angle measurement illustrated the sulfonated PPNWF owning good hydrophilicity. The in vitro hemocompatibility evaluation showed that both PP-g-P(AA-co-NaSS) and PP-g-P(AAm-co-NaSS) inhibited effectively the adhesion of platelets and were significantly compatible with erythrocytes. Moreover, no obvious difference was confirmed in the prevention of platelet adhesion and hemolysis ratio between carboxyl and amide groups. However, as compared with that of PP-g-P(AAm-co-NaSS), PP-g-P(AA-co-NaSS) exhibited outstanding anticoagulant activity via increased activated partial thromboplastin time and thrombin time. This result indicated that the carboxyl group but not amide group featured strong synergistic effect on the anticoagulant activity of sulfonated PPNWF. (C) 2017 Wiley Periodicals, Inc. |
| Keyword | Induced Graft-polymerization Anticoagulant Activity Blood Compatibility Styrene-sulfonate Heparin Chitosan Surface Biocompatibility Antibacterial Particles |
| DOI | 10.1002/APP.45915 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000417600100019 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/29048 |
| Collection | 中科院上海应用物理研究所2011-2018年 |
| Affiliation | 1.Li, R 2.Cai, XM 3.Ye, Y 4.Wu, GZ |
| Recommended Citation GB/T 7714 | Li, R,Cai, XM,Ye, Y,et al. Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2018,135(9):-. |
| APA | Li, R,Cai, XM,Ye, Y,&Wu, GZ.(2018).Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric.JOURNAL OF APPLIED POLYMER SCIENCE,135(9),-. |
| MLA | Li, R,et al."Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric".JOURNAL OF APPLIED POLYMER SCIENCE 135.9(2018):-. |
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| Influence of carboxy（1018KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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