Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate

doi:10.1021/acs.jpcb.7b05175

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	Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate
	Wang, Y ; Shen, Y ; Li, B ; Wang, S ; Zhang, JJ ; Zhang, Y ; Hu, J
	2018
Source Publication	JOURNAL OF PHYSICAL CHEMISTRY B
ISSN	1520-6106
Volume	122 Issue:2 Pages:612-617
Subtype	期刊论文
Abstract	Nanomanipulation of single DNA molecules has great potential in fundamental genetic research and clinical analysis, and is a good model system for studying the interfacial effects on physiochemical processes, which occur when manipulating the linear DNA molecules with an atomic force microscope (AFM) tip. Here, we demonstrate that AFM nanomanipulation can be carried out on DNA molecules covered by a single-layered reduced graphene oxide sheet. Nanomanipulation, which includes cutting, pushing, and sweeping operations, specific to the covered DNA molecules can be achieved in a well-controlled manner using AFM in the PeakForce Quantitative Nano-Mechanics mode. It was found that the normal force required to cut covered DNA strands is over five times greater than that required for naked strands. This technique provides a distinctive method for the construction of graphene architecture by tailoring the underlying artificial DNA nanostructures.
Keyword	Atomic-force Microscopy Graphite Oxide Mechanical-properties Biaxial Strain Nanosheets Patterns
DOI	10.1021/acs.jpcb.7b05175
Indexed By	SCI
Language	英语
WOS ID	WOS:000423140600026
Citation statistics
Document Type	期刊论文
Identifier	http://ir.sinap.ac.cn/handle/331007/29079
Collection	中科院上海应用物理研究所2011-2020年
Affiliation	1.Wang, Y 2.Shen, Y 3.Li, B 4.Wang, S 5.Zhang, JJ 6.Zhang, Y 7.Hu, J
Recommended Citation GB/T 7714	Wang, Y,Shen, Y,Li, B,et al. Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2018,122(2):612-617.
APA	Wang, Y.,Shen, Y.,Li, B.,Wang, S.,Zhang, JJ.,...&Hu, J.(2018).Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate.JOURNAL OF PHYSICAL CHEMISTRY B,122(2),612-617.
MLA	Wang, Y,et al."Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate".JOURNAL OF PHYSICAL CHEMISTRY B 122.2(2018):612-617.

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