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| Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate | |
| Wang, Y; Shen, Y; Li, B; Wang, S; Zhang, JJ; Zhang, Y; Hu, J | |
| 2018 | |
| Source Publication | JOURNAL OF PHYSICAL CHEMISTRY B
 |
| ISSN | 1520-6106 |
| Volume | 122Issue:2Pages:612-617 |
| Subtype | 期刊论文 |
| Abstract | Nanomanipulation of single DNA molecules has great potential in fundamental genetic research and clinical analysis, and is a good model system for studying the interfacial effects on physiochemical processes, which occur when manipulating the linear DNA molecules with an atomic force microscope (AFM) tip. Here, we demonstrate that AFM nanomanipulation can be carried out on DNA molecules covered by a single-layered reduced graphene oxide sheet. Nanomanipulation, which includes cutting, pushing, and sweeping operations, specific to the covered DNA molecules can be achieved in a well-controlled manner using AFM in the PeakForce Quantitative Nano-Mechanics mode. It was found that the normal force required to cut covered DNA strands is over five times greater than that required for naked strands. This technique provides a distinctive method for the construction of graphene architecture by tailoring the underlying artificial DNA nanostructures. |
| Keyword | Atomic-force Microscopy Graphite Oxide Mechanical-properties Biaxial Strain Nanosheets Patterns |
| DOI | 10.1021/acs.jpcb.7b05175 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000423140600026 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sinap.ac.cn/handle/331007/29079 |
| Collection | 中科院上海应用物理研究所2011-2018年 |
| Affiliation | 1.Wang, Y 2.Shen, Y 3.Li, B 4.Wang, S 5.Zhang, JJ 6.Zhang, Y 7.Hu, J |
| Recommended Citation GB/T 7714 | Wang, Y,Shen, Y,Li, B,et al. Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2018,122(2):612-617. |
| APA | Wang, Y.,Shen, Y.,Li, B.,Wang, S.,Zhang, JJ.,...&Hu, J.(2018).Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate.JOURNAL OF PHYSICAL CHEMISTRY B,122(2),612-617. |
| MLA | Wang, Y,et al."Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate".JOURNAL OF PHYSICAL CHEMISTRY B 122.2(2018):612-617. |
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| Nanomanipulation of （5459KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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