Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate

doi:10.1021/acs.jpcb.7b05175

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	Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate
	Wang, Y ; Shen, Y ; Li, B ; Wang, S ; Zhang, JJ ; Zhang, Y ; Hu, J
	2018
发表期刊	JOURNAL OF PHYSICAL CHEMISTRY B
ISSN	1520-6106
卷号	122 期号:2 页码:612-617
文章类型	期刊论文
摘要	Nanomanipulation of single DNA molecules has great potential in fundamental genetic research and clinical analysis, and is a good model system for studying the interfacial effects on physiochemical processes, which occur when manipulating the linear DNA molecules with an atomic force microscope (AFM) tip. Here, we demonstrate that AFM nanomanipulation can be carried out on DNA molecules covered by a single-layered reduced graphene oxide sheet. Nanomanipulation, which includes cutting, pushing, and sweeping operations, specific to the covered DNA molecules can be achieved in a well-controlled manner using AFM in the PeakForce Quantitative Nano-Mechanics mode. It was found that the normal force required to cut covered DNA strands is over five times greater than that required for naked strands. This technique provides a distinctive method for the construction of graphene architecture by tailoring the underlying artificial DNA nanostructures.
关键词	Atomic-force Microscopy Graphite Oxide Mechanical-properties Biaxial Strain Nanosheets Patterns
DOI	10.1021/acs.jpcb.7b05175
收录类别	SCI
语种	英语
WOS记录号	WOS:000423140600026
引用统计
文献类型	期刊论文
条目标识符	http://ir.sinap.ac.cn/handle/331007/29079
专题	中科院上海应用物理研究所2011-2018年
作者单位	1.Wang, Y 2.Shen, Y 3.Li, B 4.Wang, S 5.Zhang, JJ 6.Zhang, Y 7.Hu, J
推荐引用方式 GB/T 7714	Wang, Y,Shen, Y,Li, B,et al. Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2018,122(2):612-617.
APA	Wang, Y.,Shen, Y.,Li, B.,Wang, S.,Zhang, JJ.,...&Hu, J.(2018).Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate.JOURNAL OF PHYSICAL CHEMISTRY B,122(2),612-617.
MLA	Wang, Y,et al."Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate".JOURNAL OF PHYSICAL CHEMISTRY B 122.2(2018):612-617.

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